1H-Benzimidazole,1-methoxy-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazole,1-methoxy-(9CI)
• CAS No.: 6595-08-0
• Molecular Formula: C8H8N2O
• Molecular Weight: 148.164
• Mol file: 6595-08-0.mol

Synonyms:Benzimidazole,1-methoxy- (7CI,8CI);1-Methoxybenzimidazole;

Chemical Property of 1H-Benzimidazole,1-methoxy-(9CI)

Chemical Property:

• Vapor Pressure: 0.017mmHg at 25°C
• Refractive Index: 1.594
• Boiling Point: 254.191 °C at 760 mmHg
• PKA: 3.43±0.10(Predicted)
• Flash Point: 107.531 °C
• Density: 1.182 g/cm³

Purity/Quality:

98%Min ^*data from raw suppliers

1-METHOXY-1H-BENZIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Benzimidazole,1-methoxy-(9CI)

There total 1 articles about 1H-Benzimidazole,1-methoxy-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + fuberidazole (3878-19-1) → benzoimidazole (51-17-2,79351-71-6) + 2-benzimidazolecarboxylic acid (2849-93-6) + BICA methyl ester (5805-53-8) + 2,2'-bi-1H-benzimidazole (6965-02-2) + methyl 4-oxo-2-benzimidazolecrotonate + 1-methoxy-benzimidazole (6595-08-0)

Guidance literature:

Product distribution; Mechanism; Quantum yield; Irradiation; reaction in acidic CH₃OH/H₂O at pH 3.0;

Reference yield:

1-methoxy-benzimidazole (6595-08-0) → 1,3-dihydro-2H-benzimidazol-2-one (615-16-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 1 h

2: 60 percent / water / 5 h / Heating

With water; In diethyl ether;

DOI:10.1007/BF00506589

Reference yield:

1-methoxy-benzimidazole (6595-08-0) → 1-ethoxymethyl-2-aminobenzimidazole (83750-32-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 1 h

2: 62 percent / liquid ammonia / 1 h / -78 °C

With ammonia; In diethyl ether;

DOI:10.1007/BF00506589

upstream raw materials:

methanol

fuberidazole

Downstream raw materials:

1,3-dihydro-2H-benzimidazol-2-one

1-ethoxymethyl-2-aminobenzimidazole

Refernces