trans-3-(Trimethylsilyl)allyl alcohol

Base Information

• Chemical Name: trans-3-(Trimethylsilyl)allyl alcohol
• CAS No.: 59376-64-6
• Molecular Formula: C6H14OSi
• Molecular Weight: 130.262
• European Community (EC) Number: 622-682-4
• Nikkaji Number: J441.033E
• Mol file: 59376-64-6.mol

Synonyms:trans-3-(Trimethylsilyl)allyl alcohol;59376-64-6;(E)-3-(trimethylsilyl)prop-2-en-1-ol;(E)-3-trimethylsilylprop-2-en-1-ol;52685-39-9;Trimethylsilyl-2-propen-1-ol;2-Propen-1-ol, 3-(trimethylsilyl)-;trans-3-(Trimethylsilyl)-2-propen-1-ol;MFCD00134422;3-(trimethylsilyl)allylalcohol;SCHEMBL2172402;AMY1235;BRTBTJVSPJZQIT-GQCTYLIASA-N;AKOS015909058;(E)-3-(Trimethylsilyl)-2-propen-1-ol;DS-11396;(2E)-3-(Trimethylsilyl)-2-propen-1-ol;(2E)-3-(trimethylsilyl)prop-2-en-1-ol;(2E)-3-(Trimethylsilyl)-2-propen-1-ol #;A829203;A832288;J-802119

Chemical Property of trans-3-(Trimethylsilyl)allyl alcohol

Chemical Property:

• Vapor Pressure: 0.574mmHg at 25°C
• Refractive Index: n20/D 1.444(lit.)
• Boiling Point: 167 °C at 760 mmHg
• PKA: 14.67±0.10(Predicted)
• Flash Point: 63.3 °C
• PSA: 20.23000
• Density: 0.843 g/cm³
• LogP: 2.39630
• Storage Temp.: −20°C
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 130.081391600
• Heavy Atom Count: 8
• Complexity: 81

Purity/Quality:

99% ^*data from raw suppliers

trans-3-(Trimethylsilyl)allyl alcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)C=CCO
• Isomeric SMILES: C[Si](C)(C)/C=C/CO
• Uses: trans-3-(Trimethylsilyl)allyl alcohol is suitable for use in the preparation of 1-iodo-3-trimethylsilyl-2-propene, via mesylation followed by iodide displacement.

Technology Process of trans-3-(Trimethylsilyl)allyl alcohol

There total 23 articles about trans-3-(Trimethylsilyl)allyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-trimethylsilyl-2-propyn-1-ol (5272-36-6) → (2E)-3-(trimethylsilyl)prop-2-en-1-ol (59376-64-6)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo00255a007

Reference yield: 100.0%

3-trimethylsilyl-2-propyn-1-ol (5272-36-6) → 3-(trimethylsilyl)allyl alcohol (59376-64-6,62861-80-7,52685-39-9)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In diethyl ether; at 20 ℃; for 0.5h;

DOI:10.1039/c5cc01899d

Reference yield: 97.0%

(E)-3-(trimethylsilyl)-2-propen-1-yl methyl carbonate (126333-26-4) → (2E)-3-(trimethylsilyl)prop-2-en-1-ol (59376-64-6)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/jo00031a002

upstream raw materials:

3-trimethylsilyl-2-propyn-1-ol

(E)-3-trimethylsilyl-2-propenal

Tris(trimethylsilyl)aluminium

propargyl alcohol

Downstream raw materials:

<<2-<(3-(trimethylsilyl)-2-propenyl)oxy>-2-propenyl>sulfonyl>benzene

2-<(E)-<<(E)-3-(trimethylsilyl)allyl>oxy>methylene>cyclohexanone

(E)-3-bromo-1-(trimethylsilyl)propene

trans-1-(trimethylsilyl)-3-phenyl-1-propene

Refernces

• 1、 Bowen, James I.,Crump, Matthew P.,Wang, Luoyi,Willis, Christine L.. "Ambruticins: tetrahydropyran ring formation and total synthesis". supporting information. p. 6210 - 6215. Retrieved 2021/07/28.
• 2、 Amer, Mostafa M.,Olaizola, Olatz,Carter, Jennifer,Abas, Hossay,Clayden, Jonathan. "An Aliphatic Bischler-Napieralski Reaction: Dihydropyridones by Cyclocarbonylation of 3-Allylimidazolidin-4-ones". supporting information. p. 253 - 256. Retrieved 2020/01/02.