N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE

Base Information

• Chemical Name: N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE
• CAS No.: 40861-08-3
• Molecular Formula: C14H13Cl2NO
• Molecular Weight: 282.169
• Hs Code.: 2928000090
• Mol file: 40861-08-3.mol

Synonyms:Bis(4-chlorobenzyl)hydroxylamine;N,N-Bis(p-chlorobenzyl)hydroxylamine;

Chemical Property of N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE

Chemical Property:

• Vapor Pressure: 2.63E-08mmHg at 25°C
• Refractive Index: 1.63
• Boiling Point: 434.1 °C at 760 mmHg
• Flash Point: 216.4 °C
• PSA: 23.47000
• Density: 1.333g/cm³
• LogP: 4.38480

Purity/Quality:

98%min ^*data from raw suppliers

N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE

There total 3 articles about N,N-DI(4-CHLOROBENZYL)HYDROXYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

1-Chloro-4-(chloromethyl)benzene (104-83-6) → N,N-bis(p-chlorobenzyl)hydroxylamine (40861-08-3)

Guidance literature:

With hydroxylamine hydrochloride; sodium carbonate; In ethanol; at 85 ℃; for 2h;

DOI:10.1002/adsc.201600308

Reference yield:

4-chlorobenzylamine (104-86-9) → 4-Cyanochlorobenzene (623-03-0) + N,N-bis(p-chlorobenzyl)hydroxylamine (40861-08-3) + 4-chlorobenzaldehyde (104-88-1)

Guidance literature:

With sodium hypochlorite; at 75 ℃; for 5h; Autoclave;

DOI:10.1039/c5cc09463a

Reference yield:

10-methylacridinyl radical (1226954-85-3) + C14H13Cl2NO(1+)*ClO4(1-) → N,N-bis(p-chlorobenzyl)hydroxylamine (40861-08-3) + 10-methylacridinium perchlorate (26456-05-3)

Guidance literature:

With oxygen; In acetonitrile; at 20 ℃; Further Variations:; relative rate constants (vs. N,N-dibenzylhydroxylamine); Thermodynamic data;

DOI:10.1039/b009206l

upstream raw materials:

1-Chloro-4-(chloromethyl)benzene

10-methylacridinyl radical

4-chlorobenzylamine

Downstream raw materials:

[Ph₃PCH₂Ph][PtCl₃(NH=C(Et)ON(CH₂C₆H₄Cl-p)2)]

cis-[Re(IV)Cl₄(NH=C(Me)ON(p-CH₂C₆H₄Cl)2)2]

trans-[PtCl₂(NH=C(Et)ON(CH₂C₆H₄Cl-p)2)2]

cis-[PtCl₂(NH=C(Et)ON(CH₂C₆H₄Cl-p)2)2]

Refernces

• 1、 Primo, Ana,Puche, Marta,Pavel, Octavian D.,Cojocaru, Bogdan,Tirsoaga, Alina,Parvulescu, Vasile,García, Hermenegildo. "Graphene oxide as a metal-free catalyst for oxidation of primary amines to nitriles by hypochlorite". . p. 1839 - 1842. Retrieved 2016/02/12.
• 2、 Andoh, Fumihiko,Kubo, Kanji,Sakurai, Tadamitsu. "Imine-forming radical elimination reactions of O-(1-naphthoyl)-N,N- bis(p-substituted benzyl)hydroxylamines activated by triplet benzophenone". . p. 2537 - 2542. Retrieved 2007/10/03.