(R)-2-Aminoheptanoic acid

Base Information

• Chemical Name: (R)-2-Aminoheptanoic acid
• CAS No.: 44902-01-4
• Molecular Formula: C₇H₁₅NO₂
• Molecular Weight: 145.202
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID30415623
• Nikkaji Number: J72.163H
• Wikidata: Q27144078
• Metabolomics Workbench ID: 1846
• Mol file: 44902-01-4.mol

Synonyms:(R)-2-Aminoheptanoic acid;44902-01-4;(2R)-2-aminoheptanoic acid;2R-aminoheptanoic acid;(2R)-aminoheptanoic acid;Heptanoic acid, 2-amino-, (R)-;R-2-Aminoheptanoic acid;(R)-2-Aminoheptanoicacid;(?)-Heptyline;H-D-Ahp(2)-OH;SCHEMBL2730539;CHEBI:73738;DTXSID30415623;RDFMDVXONNIGBC-ZCFIWIBFSA-N;LMFA01100013;MFCD08275758;DS-3409;CS-0152364;C75217;EN300-731684;(2R)-2-Amino-heptanoic acid (H-D-Nle(Me)-OH);Q27144078

Chemical Property of (R)-2-Aminoheptanoic acid

Chemical Property:

• Boiling Point: 251.0±23.0 °C(Predicted)
• PKA: 2.55±0.24(Predicted)
• PSA: 63.32000
• Density: 1.017±0.06 g/cm3(Predicted)
• LogP: 1.67890
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: -1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 145.110278721
• Heavy Atom Count: 10
• Complexity: 104

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-Aminoheptanoicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC(C(=O)O)N
• Isomeric SMILES: CCCCC[C@H](C(=O)O)N

Technology Process of (R)-2-Aminoheptanoic acid

There total 10 articles about (R)-2-Aminoheptanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-2-<(benzyloxycarbonyl)amino>heptanoic Acid → (R)-2-aminoheptanoic acid (44902-01-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water; acetic acid;

DOI:10.1021/ja00249a031

Reference yield:

2-oxoheptanoic acid (13088-48-7) → (R)-2-aminoheptanoic acid (44902-01-4)

Guidance literature:

With meso-2,6-D-diaminopimelic acid dehydrogenase mutant BC₆₂₁; ammonium chloride; NADPH; In various solvent(s); for 24h;

DOI:10.1021/ja0603960

Reference yield:

→ (R)-2-aminoheptanoic acid (44902-01-4)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01147a144

upstream raw materials:

2-oxoheptanoic acid

2-aminoheptanoic acid

1-Bromopentane

diethyl n-pentylmalonate

Refernces

• 1、 Miyazawa, Toshifumi,Imagawa, Kiwamu,Minowa, Hiroe,Miyamoto, Toyoko,Yamada, Takashi. "Resolution of non-protein amino acids via the microbial protease-catalyzed enantioselective hydrolysis of their N-unprotected esters". . p. 10254 - 10261. Retrieved 2007/10/03.