N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANYL CHLORIDE

Base Information

• Chemical Name: N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANYL CHLORIDE
• CAS No.: 146864-62-2
• Molecular Formula: C₁₉H₁₆ClNO₃S
• Molecular Weight: 373.86
• Hs Code.: 2935009090
• Mol file: 146864-62-2.mol

Synonyms:Benzenepropanoylchloride, a-[(1-naphthalenylsulfonyl)amino]-,(S)-; N-(1-Naphthalenesulfonyl)-L-phenylalanyl chloride

Chemical Property of N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANYL CHLORIDE

Chemical Property:

• Melting Point: 104 °C
• Refractive Index: 19 ° (C=2, Dioxane)
• PSA: 71.62000
• LogP: 4.96650

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(1-Naphthalenesulfonyl)-L-phenylalanyl Chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANYL CHLORIDE

There total 3 articles about N-(1-NAPHTHALENESULFONYL)-L-PHENYLALANYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → 2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionyl chloride (90291-51-3,146864-62-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / 1 mol/l NaOH / diethyl ether; H₂O

2: SOCl₂ / 1 h / Heating

With sodium hydroxide; thionyl chloride; In diethyl ether; water;

Reference yield:

1-Naphthalenesulfonyl chloride (85-46-1) → 2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionyl chloride (90291-51-3,146864-62-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / 1 mol/l NaOH / diethyl ether; H₂O

2: SOCl₂ / 1 h / Heating

With sodium hydroxide; thionyl chloride; In diethyl ether; water;

Reference yield:

2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionic acid (90291-46-6) → 2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionyl chloride (90291-51-3,146864-62-2)

Guidance literature:

With thionyl chloride; for 1h; Heating;

upstream raw materials:

2-(Naphthalene-1-sulfonylamino)-3-phenyl-propionic acid

Phenylalanine

1-Naphthalenesulfonyl chloride

Refernces