2-Piperazinemethanol

Base Information

• Chemical Name: 2-Piperazinemethanol
• CAS No.: 28795-50-8
• Molecular Formula: C5H12N2O
• Molecular Weight: 116.163
• Hs Code.: 2933599090
• Mol file: 28795-50-8.mol

Synonyms:2-(Hydroxymethyl)piperazine;

Chemical Property of 2-Piperazinemethanol

Chemical Property:

• Vapor Pressure: 0.01mmHg at 25°C
• Melting Point: 95-96 °C
• Refractive Index: 1.448
• Boiling Point: 234.479 °C at 760 mmHg
• PKA: 14.97±0.10(Predicted)
• Flash Point: 125.639 °C
• PSA: 44.29000
• Density: 0.992 g/cm³
• LogP: -0.80230

Purity/Quality:

98%min ^*data from raw suppliers

(Piperazin-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (Piperazin-2-yl)methanol is a useful compound in the chemical process of acidic gas removal.

Technology Process of 2-Piperazinemethanol

There total 3 articles about 2-Piperazinemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.98%

piperazine-2-carboxylic acid dihydrochloride (3022-15-9,126330-90-3,133525-05-0,135841-26-8) → 2-hydroxymethylpiperazine (28795-50-8)

Guidance literature:

With lithium aluminium tetrahydride; sodium hydroxide; In tetrahydrofuran; at 0 - 70 ℃; for 18h; Inert atmosphere;

Reference yield:

N-(2,3-dihydroxypropyl)-ethylenediamine (60095-23-0) → piperazine (110-85-0) + 2-hydroxymethylpiperazine (28795-50-8) + ethylenediamine (107-15-3,85404-18-8)

Guidance literature:

monoaluminum phosphate; In water; at 300 ℃; Product distribution / selectivity;

Reference yield:

N-(1,3-dihydroxyprop-2-yl)ethylenediamine (89416-75-1) → piperazine (110-85-0) + 2-hydroxymethylpiperazine (28795-50-8) + ethylenediamine (107-15-3,85404-18-8)

Guidance literature:

monoaluminum phosphate; In water; at 280 ℃; for 2h; Product distribution / selectivity; Inert atmosphere; Autoclave;

upstream raw materials:

N-(2,3-dihydroxypropyl)-ethylenediamine

N-(1,3-dihydroxyprop-2-yl)ethylenediamine

piperazine-2-carboxylic acid dihydrochloride

Downstream raw materials:

4-Acetyl-2-piperazinemethanol

methyl 3-(hydroxymethyl)-1-piperazinecarboxylate

Refernces

• 1、 -. "PROCESS FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND, AND CATALYST COMPOSITION FOR THE PRODUCTION OF POLYURETHANE RESIN USING THE HYDROXYALKYLTRIETHYLENEDIAMINE COMPOUND". Page/Page column 29. . Retrieved 2011/04/18.