TERT-BUTYL 3-BUTENOATE

Base Information

• Chemical Name: TERT-BUTYL 3-BUTENOATE
• CAS No.: 14036-55-6
• Molecular Formula: C8H14O2
• Molecular Weight: 142.198
• Hs Code.: 29161900
• Mol file: 14036-55-6.mol

Synonyms:tert-butyl but-3-enoate;

Chemical Property of TERT-BUTYL 3-BUTENOATE

Chemical Property:

• Vapor Pressure: 3.22mmHg at 25°C
• Refractive Index: n20/D 1.413
• Boiling Point: 154.1 °C at 760 mmHg
• Flash Point: 49.9 °C
• PSA: 26.30000
• Density: 0.893 g/cm³
• LogP: 1.90420
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

tert-Butyl 3-butenoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 10-22-36/37/38
• Safety Statements: 26

MSDS Files:

Useful:

Technology Process of TERT-BUTYL 3-BUTENOATE

There total 16 articles about TERT-BUTYL 3-BUTENOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

but-3-enoic acid (625-38-7) + acetic acid tert-butyl ester (540-88-5) → t-butyl vinylacetate (14036-55-6)

Guidance literature:

With boron trifluoride diethyl etherate; at 20 ℃; for 48h;

DOI:10.1021/jacs.6b01327

Reference yield: 75.0%

trans-chrotonyl chloride (625-35-4,3488-22-0,10487-71-5) + tert-butyl alcohol (75-65-0) → t-butyl vinylacetate (14036-55-6)

Guidance literature:

With triethylamine; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jo301066p

Reference yield: 58.0%

but-3-enoic acid (625-38-7) + tert-Butyl 2,2,2-trichloroacetimidate (98946-18-0) → t-butyl vinylacetate (14036-55-6)

Guidance literature:

In dichloromethane; at 20 ℃; for 24h;

DOI:10.1021/es0620181

upstream raw materials:

C₁₂H₁₆N₂O₄S

(E)-tert-butyl 4-bromobut-2-enoate

crotonyl chloride

tert-butyl alcohol

Refernces

• 1、 Boots,Boots. "New synthesis of (RS) carnitine chloride". . p. 1262 - 1264. Retrieved 1975.
• 2、 Brückner, Reinhard,Kopp, Julia. "Stereoselective Total Synthesis of the Dimeric Naphthoquinonopyrano-?-lactone (-)-Crisamicin A: Introducing the Dimerization Site by a Late-Stage Hartwig Borylation". . . Retrieved 2020.
• 3、 Mahajani, Nivedita S.,Meador, Rowan I. L.,Smith, Tomas J.,Canarelli, Sarah E.,Adhikari, Arijit A.,Shah, Jigisha P.,Russo, Christopher M.,Wallach, Daniel R.,Howard, Kyle T.,Millimaci, Alexandra M.,Chisholm, John D.. "Ester Formation via Symbiotic Activation Utilizing Trichloroacetimidate Electrophiles". . p. 7871 - 7882. Retrieved 2019/06/27.