mono-tert-Butyl succinate

Base Information Edit

Chemical Name:mono-tert-Butyl succinate
CAS No.:15026-17-2
Molecular Formula:C8H14O4
Molecular Weight:174.197
Hs Code.:2918990090
European Community (EC) Number:628-576-4
DSSTox Substance ID:DTXSID90399798
Nikkaji Number:J737.515H
Wikidata:Q72492651
Mol file:15026-17-2.mol

Synonyms:mono-tert-Butyl succinate;15026-17-2;4-(tert-Butoxy)-4-oxobutanoic acid;Succinic acid mono-tert-butyl ester;4-tert-butoxy-4-oxobutanoic acid;4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid;tert-butyl hydrogen succinate;MFCD00273441;mono-t-butyl succinate;SCHEMBL631111;mono-tert-Butyl succinate, 97%;DTXSID90399798;Succinic acid 1-tert-butyl ester;succinic acid 4-tert-butyl ester;PCOCFIOYWNCGBM-UHFFFAOYSA-N;AKOS015918068;CS-W008838;AS-19219;BP-20383;SY031819;FT-0650778;M3033;Butanedioic acid 1-(1,1-dimethylethyl) ester;EN300-114582;J-008675

Suppliers and Price of mono-tert-Butyl succinate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Mono-tert-butyl Succinate
5g
$ 65.00

TCI Chemical
Mono-tert-butyl Succinate >98.0%(GC)(T)
1g
$ 23.00

TCI Chemical
Mono-tert-butyl Succinate >98.0%(GC)(T)
5g
$ 92.00

SynQuest Laboratories
Mono-tert-butyl succinate
2 g
$ 168.00

Sigma-Aldrich
mono-tert-Butyl succinate 97%
5g
$ 145.00

Crysdot
4-(tert-Butoxy)-4-oxobutanoicacid 97+%
100g
$ 272.00

Chem-Impex
Mono-tert-butylsuccinate,≥99%(GC) ≥99%(GC)
250G
$ 453.69

Chem-Impex
Mono-tert-butylsuccinate,99%(GC) 99%(GC)
100G
$ 244.72

Chem-Impex
Mono-tert-butylsuccinate,99%(GC) 99%(GC)
25G
$ 79.80

Chem-Impex
Mono-tert-butylsuccinate,99%(GC) 99%(GC)
1G
$ 10.64

Total 56 raw suppliers

Chemical Property of mono-tert-Butyl succinate Edit

Chemical Property:

Vapor Pressure:0.00169mmHg at 25°C
Melting Point:51-54 ºC
Refractive Index:1.447
Boiling Point:272.4°Cat760mmHg
PKA:4.46±0.17(Predicted)
Flash Point:110 ºC
PSA：63.60000
Density:1.097g/cm³
LogP:1.19290
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), Methanol (Sparingly)
Water Solubility.:Slightly soluble in water.
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:174.08920892
Heavy Atom Count:12
Complexity:178

Purity/Quality:

99% ^*data from raw suppliers

Mono-tert-butyl Succinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CCC(=O)O
Uses Mono-tert-butyl Succinate is a reagent used for the synthesis of fluorinated β2- and β3-amino acids, an inhibitor of α-chymotrypsin.

Technology Process of mono-tert-Butyl succinate

There total 17 articles about mono-tert-Butyl succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 108-30-5
succinic acid anhydride

: 75-65-0
tert-butyl alcohol

: 15026-17-2
succinic acid mono-tert-butyl ester

Guidance literature:: With dmap; 1-hydroxy-pyrrolidine-2,5-dione; In toluene; for 48h; Reflux;
DOI:10.3762/bjoc.13.240

Reference yield: 89.0%

: (1-nosyl-5-nitroindol-3-yl)methyl tert-butyl succinate

: 15026-17-2
succinic acid mono-tert-butyl ester

Guidance literature:: (1-nosyl-5-nitroindol-3-yl)methyl tert-butyl succinate; With 2-(N,N-dimethylamino)ethylthiol hydrochloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 0.25h; Inert atmosphere;

With hydrogenchloride; In diethyl ether; water; acetonitrile; Inert atmosphere;
DOI:10.1021/ol8008655