4-(Allyloxy)phenol

Base Information

• Chemical Name: 4-(Allyloxy)phenol
• CAS No.: 6411-34-3
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Hs Code.: 2909500000
• DSSTox Substance ID: DTXSID10364887
• Nikkaji Number: J260.179F
• Wikidata: Q72437364
• Mol file: 6411-34-3.mol

Synonyms:4-(allyloxy)phenol;6411-34-3;4-Allyloxyphenol;4-prop-2-enoxyphenol;4-(prop-2-en-1-yloxy)phenol;4-ALLYLOXY-PHENOL;Phenol, 4-(2-propenyloxy)-;SCHEMBL261038;DTXSID10364887;BCP27169;AKOS005145973;AM20040940;FT-0689954;EN300-91576;A15725;AK-087/42718133;A1-10090;Z381414818

Chemical Property of 4-(Allyloxy)phenol

Chemical Property:

• Vapor Pressure: 0.00361mmHg at 25°C
• Refractive Index: 1.538
• Boiling Point: 272.6 °C at 760 mmHg
• Flash Point: 146 °C
• PSA: 29.46000
• Density: 1.072 g/cm³
• LogP: 1.95700
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 150.068079557
• Heavy Atom Count: 11
• Complexity: 115

Purity/Quality:

99.5% ^*data from raw suppliers

4-(allyloxy)phenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCOC1=CC=C(C=C1)O
• Use Description: 4-Allyloxyphenol is a versatile chemical compound with applications in various fields. In the field of materials science and polymer chemistry, it serves as a key monomer for the synthesis of polymers and resins with unique properties, such as heat resistance and adhesion strength. Its role is pivotal in the development of specialty materials used in coatings, adhesives, and plastics, contributing to the production of durable and high-performance products. Additionally, in the pharmaceutical and organic chemistry sectors, 4-allyloxyphenol can be utilized as a reagent and building block for the synthesis of organic compounds and pharmaceutical intermediates, making it valuable for drug discovery and chemical research. Furthermore, in the academic and industrial research laboratories, this compound can be employed as a reference compound for studying the chemistry of allyloxyphenols and their reactivity, aiding in the advancement of synthetic methodologies and chemical understanding. Its multifaceted utility underscores its significance in advancing materials technology, chemical synthesis, and scientific research, where it plays a crucial role in material development, compound synthesis, and chemical investigation.

Technology Process of 4-(Allyloxy)phenol

There total 24 articles about 4-(Allyloxy)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,4-bis(allyloxy)benzene (37592-20-4) → 4-allyloxyphenol (6411-34-3)

Guidance literature:

With ethylmagnesium chloride; iron(II) chloride; In tetrahydrofuran; m-xylene; at 20 ℃; for 1h;

DOI:10.1039/c3cy00266g

Reference yield: 92.0%

allyl bromide (106-95-6) + hydroquinone (123-31-9,8027-02-9) → 4-allyloxyphenol (6411-34-3)

Guidance literature:

With potassium carbonate; In acetonitrile; for 12h; Heating;

DOI:10.1016/S0968-0896(03)00362-6

Reference yield: 91.0%

1-allyloxy-4-prop-2-ynyloxy-benzene (153164-85-3) → 4-allyloxyphenol (6411-34-3)

Guidance literature:

With titanium(IV) isopropylate; chloro-trimethyl-silane; magnesium; In tetrahydrofuran; ethyl acetate; at 20 ℃; for 26h;

DOI:10.1021/ol062963u

upstream raw materials:

allyl bromide

hydroquinone

allyltributylstanane

p-benzoquinone

Downstream raw materials:

2-allylhydroquinone

4-allyloxyphenyl methylthiomethyl ether

4-propoxyphenol

hydroquinone

Refernces

• 1、 Gautier, Arnaud,Mulatier, Jean-Christophe,Crassous, Jeanne,Dutasta, Jean-Pierre. "Chiral trialkanolamine-based hemicryptophanes: Synthesis and oxovanadium complex". . p. 1207 - 1210. Retrieved 2005.
• 2、 Ding, Guangni,Fan, Sijie,Wang, Jingyang,Wang, Yu,Wu, Xiaoyu,Xie, Xiaomin,Yang, Liqun,Zhang, Zhaoguo. "Nickel-catalyzed deallylation of aryl allyl ethers with hydrosilanes". supporting information. . Retrieved 2021/09/28.
• 3、 -. "CELL CYCLE PROGRESSION INHIBITOR". Paragraph 0086. . Retrieved 2019/09/18.