Technology Process of C30H29NO3S
There total 4 articles about C30H29NO3S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-iodo-1-tosyl-1-indole;
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine;
at 23 ℃;
for 0.0833333h;
Inert atmosphere;
C15H18O;
In
tetrahydrofuran;
at 23 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ol400625f
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Noyori's catalyst / isopropyl alcohol / 48 h / 23 °C / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 4.33 h / 0 - 23 °C / Inert atmosphere
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 0 - 23 °C / Inert atmosphere
4.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / 0.08 h / 23 °C / Inert atmosphere
4.2: 3 h / 23 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; Noyori's catalyst; tetrabutyl ammonium fluoride; sodium hydride; diisopropylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; isopropyl alcohol; mineral oil;
1.1: |Noyori Asymmetric Hydrogenation;
DOI:10.1021/ol400625f
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 4.33 h / 0 - 23 °C / Inert atmosphere
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 0 - 23 °C / Inert atmosphere
3.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / 0.08 h / 23 °C / Inert atmosphere
3.2: 3 h / 23 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrabutyl ammonium fluoride; sodium hydride; diisopropylamine;
In
tetrahydrofuran; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ol400625f