N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine

Base Information

• Chemical Name: N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine
• CAS No.: 248599-61-3
• Molecular Formula: C₂₄H₂₄N₄O₈
• Molecular Weight: 496.477
• Mol file: 248599-61-3.mol

Synonyms:N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine

Chemical Property of N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine

There total 7 articles about N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-<2-(4-nitrophenyl)ethyl>acetamide (6270-07-1) → N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine (248599-61-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / 47percent HBr / 6 h / Heating

2: 81.5 percent / K₂CO₃ / acetonitrile / 20 °C

3: K₂CO₃ / acetonitrile / Heating

With potassium carbonate; In acetonitrile;

DOI:10.1021/jm010574u

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine (248599-61-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaOH; TBA / ethanol / 0.25 h / Heating

1.2: 46.8 percent / ethanol / 24 h / Heating

2.1: 81.5 percent / K₂CO₃ / acetonitrile / 20 °C

3.1: K₂CO₃ / acetonitrile / Heating

With sodium hydroxide; potassium carbonate; tert-butylamine; In ethanol; acetonitrile;

DOI:10.1021/jm010574u

Reference yield:

methyl-N-(benzyl-methyl)-formamide (877-95-2) → N-[2-(p-nitrophenoxy)ethyl]-N-[2-(p-nitrophenoxy)ethyl]-p-nitrophenethylamine (248599-61-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 76 g / conc. H₂SO₄; conc. HNO₃ / 2 h

2: 99 percent / 47percent HBr / 6 h / Heating

3: 81.5 percent / K₂CO₃ / acetonitrile / 20 °C

4: K₂CO₃ / acetonitrile / Heating

With sulfuric acid; nitric acid; potassium carbonate; In acetonitrile;

DOI:10.1021/jm010574u

upstream raw materials:

1-(2-bromoethoxy)-4-nitrobenzene

[2-(4-nitrophenyl)ethyl]{2-[(4-nitrophenyl)oxy]ethyl}amine

4-nitro-phenol

methyl-N-(benzyl-methyl)-formamide

Refernces