4-FLUORO DIPHENYL SULFIDE

Base Information

• Chemical Name: 4-FLUORO DIPHENYL SULFIDE
• CAS No.: 330-85-8
• Molecular Formula: C12H9FS
• Molecular Weight: 204.268
• Hs Code.: 2930909090
• Mol file: 330-85-8.mol

Synonyms:Sulfide,p-fluorophenyl phenyl (7CI,8CI);p-Fluorophenylphenyl sulfide;4-Fluorophenyl phenyl sulfide;

Chemical Property of 4-FLUORO DIPHENYL SULFIDE

Chemical Property:

• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.621
• Boiling Point: 308.1 °C at 760 mmHg
• Flash Point: 140.1 °C
• PSA: 25.30000
• Density: 1.2 g/cm³
• LogP: 3.97690

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-FLUORO DIPHENYL SULFIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-FLUORO DIPHENYL SULFIDE

There total 54 articles about 4-FLUORO DIPHENYL SULFIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-Fluorothiophenol (371-42-6) + chlorobenzene (108-90-7) → 1-fluoro-4-(phenylthio)benzene (330-85-8)

Guidance literature:

With tetrakis(tri-p-tolylphosphite)nickel⁽⁰⁾; potassium tert-butylate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; zinc; In toluene; at 110 ℃; for 16h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.7b03560

Reference yield: 99.0%

1-Chloro-4-fluorobenzene (352-33-0) + thiophenol (108-98-5) → 1-fluoro-4-(phenylthio)benzene (330-85-8)

Guidance literature:

With tetrakis(tri-p-tolylphosphite)nickel⁽⁰⁾; potassium tert-butylate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; zinc; In toluene; at 110 ℃; for 16h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.7b03560

Reference yield: 98.0%

iodobenzene (591-50-4) + 4-Fluorothiophenol (371-42-6) → 1-fluoro-4-(phenylthio)benzene (330-85-8)

Guidance literature:

With potassium phosphate; copper(l) iodide; 2.9-dimethyl-1,10-phenanthroline; In butan-1-ol; at 120 ℃; for 2h; Microwave irradiation;

DOI:10.1002/jccs.201190064

upstream raw materials:

4-fluoro-1-iodobenzene

potassium thiophenolate

iodobenzene

4-Fluorothiophenol

Downstream raw materials:

(4-fluorophenyl)(phenyl) sulfoxide

(4-fluorophenyl)diphenylsulfonium trifluoromethanesulfonate

2-fluorodibenzothiophene

1-(4-((4-fluorophenyl)thio)phenyl)ethan-1-one

Refernces

• 1、 Pan, Lei,Cooke, Maria Victoria,Spencer, Amara,Laulhé, Sébastien. "Dimsyl Anion Enables Visible-Light-Promoted Charge Transfer in Cross-Coupling Reactions of Aryl Halides". supporting information. p. 420 - 425. Retrieved 2021/11/01.
• 2、 Cao, Han,Liu, Xuejing,Bie, Fusheng,Shi, Yijun,Han, Ying,Yan, Peng,Szostak, Michal,Liu, Chengwei. "Rh(I)-Catalyzed Intramolecular Decarbonylation of Thioesters". . p. 10829 - 10837. Retrieved 2021/07/28.