2-Bromo-2,3,3,3-tetrafluoropropanoyl chloride

Base Information

• Chemical Name: 2-Bromo-2,3,3,3-tetrafluoropropanoyl chloride
• CAS No.: 6066-45-1
• Molecular Formula: C3Br Cl F4 O
• Molecular Weight: 243.383
• Hs Code.: 2915900090
• European Community (EC) Number: 670-912-7
• DSSTox Substance ID: DTXSID00371323
• Nikkaji Number: J2.293.499F
• Mol file: 6066-45-1.mol

Synonyms:2-bromo-2,3,3,3-tetrafluoropropanoyl chloride;6066-45-1;2-Bromotetrafluoropropionyl chloride;2-Bromo-2,3,3,3-tetrafluoropropionyl chloride;SCHEMBL4852747;DTXSID00371323;LYEISECDEKRQHL-UHFFFAOYSA-N;MFCD00153723;AKOS005173360;FT-0611389;2-Bromo-2,3,3,3-tetrafluoropropanyl chloride;A832833;2,3,3,3-Tetrafluoro-2-bromopropionic acid chloride;2-bromanyl-2,3,3,3-tetrakis(fluoranyl)propanoyl chloride

Chemical Property of 2-Bromo-2,3,3,3-tetrafluoropropanoyl chloride

Chemical Property:

• Vapor Pressure: 116mmHg at 25°C
• Boiling Point: 67 °C
• PSA: 17.07000
• Density: 2.001g/cm³
• LogP: 2.37480
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 241.87572
• Heavy Atom Count: 10
• Complexity: 157

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-2,3,3,3-tetrafluoropropionyl chloride 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(=O)(C(C(F)(F)F)(F)Br)Cl

Technology Process of 2-Bromo-2,3,3,3-tetrafluoropropanoyl chloride

There total 1 articles about 2-Bromo-2,3,3,3-tetrafluoropropanoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-bromo-2,3,3,3-tetrafluoropropanoyl chloride (6066-45-1)

Guidance literature:

1-Methoxy-1,2-dibrom-pentafluor-propan, ClSO3H (S.64, 73);

DOI:10.1016/S0022-1139(00)82862-6

Reference yield: 94.0%

2-bromo-2,3,3,3-tetrafluoropropanoyl chloride (6066-45-1) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 2-bromo-2,3,3,3-tetrafluoropropanoate (722496-28-8)

Guidance literature:

With triethylamine; In diethyl ether; at 0 - 20 ℃;

DOI:10.1021/ol052897g

Reference yield: 76.0%

2-bromo-2,3,3,3-tetrafluoropropanoyl chloride (6066-45-1) + (-)-menthol (2216-51-5) → 2-Bromo-2,3,3,3-tetrafluoro-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester

Guidance literature:

With triethylamine;

DOI:10.1002/ejoc.201600837

Downstream raw materials:

benzyl 2-bromo-2,3,3,3-tetrafluoropropanoate