N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide

Base Information Edit

Chemical Name:N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide
CAS No.:790-75-0
Molecular Formula:C10H6 Cl F6 N O
Molecular Weight:305.607
Hs Code.:2924299090
European Community (EC) Number:671-276-3
DSSTox Substance ID:DTXSID80365189
Nikkaji Number:J3.539.706J
Wikidata:Q82149650
ChEMBL ID:CHEMBL4649260
Mol file:790-75-0.mol

Synonyms:790-75-0;N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide;N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline;N-(3,5-bis(trifluoromethyl)phenyl)-2-chloroacetamide;n-(chloroacetyl)-3,5-bis(trifluoromethyl)aniline;2-chloro(bis-3',5'-trifluoromethylacetanilide);Acetamide,N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-;3',5'-Bis(trifluoromethyl)-2-chloroacetanilide;SCHEMBL263685;CHEMBL4649260;DTXSID80365189;JS-092C;MFCD00077474;AKOS000103574;PD168611;CS-0197432;FT-0629698;EN300-01635;J3.539.706J;D86456;A839574;J-522988;Z56869459;N-[3,5-bis(trifluoromethyl)phenyl]-2-chloro-acetamide

Suppliers and Price of N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[3,5-bis(Trifluoromethyl)phenyl]-2-chloroacetamide
10mg
$ 45.00

SynQuest Laboratories
N-(Chloroacetyl)-3,5-bis(trifluoromethyl)aniline 98%
1 g
$ 20.00

SynQuest Laboratories
N-(Chloroacetyl)-3,5-bis(trifluoromethyl)aniline 98%
5 g
$ 64.00

Oakwood
N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline 95%
25g
$ 300.00

Oakwood
N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline 95%
1g
$ 20.00

Oakwood
N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline 95%
5g
$ 80.00

Matrix Scientific
N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloroacetamide >95%
1g
$ 151.00

Matrix Scientific
N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloroacetamide >95%
500mg
$ 118.00

Crysdot
N-(3,5-Bis(trifluoromethyl)phenyl)-2-chloroacetamide 95+%
5g
$ 315.00

Atlantic Research Chemicals
2-Chloro(bis-3'',5''-trifluoromethylacetanilide) 95%
5gm:
$ 35.35

Total 17 raw suppliers

Chemical Property of N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide Edit

Chemical Property:

Vapor Pressure:0.00148mmHg at 25°C
Melting Point:85 °C
Boiling Point:296°C at 760 mmHg
PKA:11.81±0.70(Predicted)
Flash Point:132.8°C
PSA：29.10000
Density:1.52g/cm³
LogP:3.97450
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:305.0042105
Heavy Atom Count:19
Complexity:307

Purity/Quality:

98%min ^*data from raw suppliers

N-[3,5-bis(Trifluoromethyl)phenyl]-2-chloroacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C=C1C(F)(F)F)NC(=O)CCl)C(F)(F)F

Technology Process of N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide

There total 3 articles about N-[3,5-bis(trifluoromethyl)phenyl]-2-chloroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.8%

: 79-04-9
chloroacetyl chloride

: 328-74-5
3,5-Bis-(trifluoromethyl)aniline

: 790-75-0
N-(3,5-bis-trifluoromethyl-phenyl)-2-chloro-acetamide

Guidance literature:: In acetic acid; at 0 - 20 ℃;
DOI:10.1111/j.1747-0285.2010.01017.x

Reference yield: 86.0%

: 790-75-0
N-(3,5-bis-trifluoromethyl-phenyl)-2-chloro-acetamide

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 0.166667h;

In dichloromethane; for 2h; Cooling with ice;