2-AMINO-3-NITRO-5-CHLORO-6-PICOLINE

Base Information

• Chemical Name: 2-AMINO-3-NITRO-5-CHLORO-6-PICOLINE
• CAS No.: 56960-82-8
• Molecular Formula: C₆H₆ClN₃O₂
• Molecular Weight: 187.586
• Hs Code.: 2933399090
• Mol file: 56960-82-8.mol

Synonyms:2-AMINO-3-NITRO-5-CHLORO-6-PICOLINE;6-Amino-3-bromo-5-nitro-ALPHA-picoline;2-AMino-3-Nitro-5-Chloro-6-Methyl Pyridine

Chemical Property of 2-AMINO-3-NITRO-5-CHLORO-6-PICOLINE

Chemical Property:

• Vapor Pressure: 0.000382mmHg at 25°C
• Refractive Index: 1.636
• Boiling Point: 317.6 °C at 760 mmHg
• Flash Point: 145.9 °C
• PSA: 84.73000
• Density: 1.5 g/cm³
• LogP: 2.63820
• Storage Temp.: 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

2-Amino-5-chloro-3-nitro-6-picoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-3-NITRO-5-CHLORO-6-PICOLINE

There total 3 articles about 2-AMINO-3-NITRO-5-CHLORO-6-PICOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

conc H2 SO4 + 2-amino-5-chloro-6-methylpyridine (36936-23-9) → 2-Amino-5-chlor-6-methyl-3-nitro-pyridin (56960-82-8)

Guidance literature:

With aq. NaOH; nitric acid;

Reference yield:

2-Amino-6-methylpyridine (1824-81-3) → 2-Amino-5-chlor-6-methyl-3-nitro-pyridin (56960-82-8)

Guidance literature:

Multi-step reaction with 2 steps

1: N-chloro-succinimide / hexane; N,N-dimethyl-formamide

2: aq. NaOH; nitric acid

With N-chloro-succinimide; aq. NaOH; nitric acid; In hexane; N,N-dimethyl-formamide;

Reference yield:

→ 2-Amino-5-chlor-6-methyl-3-nitro-pyridin (56960-82-8)

Guidance literature:

Aminopyridin (7), Cl2-Gas/Eg.;

DOI:10.1021/jo00863a020

upstream raw materials:

2-amino-5-chloro-6-methylpyridine

2-Amino-6-methylpyridine

Refernces