Technology Process of (E)-ethyl 6-(p-methoxyphenyl)-4-oxo-2-hexenoate
There total 5 articles about (E)-ethyl 6-(p-methoxyphenyl)-4-oxo-2-hexenoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-chloro-succinimide; silver nitrate;
In
water; acetonitrile;
at -15 ℃;
DOI:10.1021/jo01301a034
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1) Lithium diisopropylamide / THF, 1) -78 deg C, 2) r. t.
2: diisobutylaluminumhydride / tetrahydrofuran / -100 - -90 °C
3: Collins reagent / CH2Cl2
4: 1) Lithium diisopropylamide / THF, 1) -78 deg C, 2) -35 deg C
5: 55 percent / N-chlorosuccinimide / AgNO3 / acetonitrile; H2O / -15 °C
With
N-chloro-succinimide; Collins oxidation agent; diisobutylaluminium hydride; silver nitrate; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane; water; acetonitrile;
DOI:10.1021/jo01301a034
- Guidance literature:
-
Multi-step reaction with 4 steps
1: diisobutylaluminumhydride / tetrahydrofuran / -100 - -90 °C
2: Collins reagent / CH2Cl2
3: 1) Lithium diisopropylamide / THF, 1) -78 deg C, 2) -35 deg C
4: 55 percent / N-chlorosuccinimide / AgNO3 / acetonitrile; H2O / -15 °C
With
N-chloro-succinimide; Collins oxidation agent; diisobutylaluminium hydride; silver nitrate; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane; water; acetonitrile;
DOI:10.1021/jo01301a034
