6-ethoxy-2,3,4,5-tetrahydropyridine

Base Information

• Chemical Name: 6-ethoxy-2,3,4,5-tetrahydropyridine
• CAS No.: 15200-13-2
• Molecular Formula: C7H13NO
• Molecular Weight: 127.186
• Hs Code.: 2933399090
• Mol file: 15200-13-2.mol

Synonyms:2-Ethoxy-3,4,5,6-tetrahydropyridine;6-Ethoxy-2,3,4,5-tetrahydropyridine;O-Ethylvalerolactim;

Chemical Property of 6-ethoxy-2,3,4,5-tetrahydropyridine

Chemical Property:

• Appearance/Colour: Light yellow liquid
• Vapor Pressure: 1.941mmHg at 25°C
• Refractive Index: 1.488
• Boiling Point: 170.539 °C at 760 mmHg
• PKA: 8.80±0.20(Predicted)
• Flash Point: 47.569 °C
• PSA: 21.59000
• Density: 1.003 g/cm³
• LogP: 1.04090
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

6-Ethoxy-2,3,4,5-tetrahydropyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-ethoxy-2,3,4,5-tetrahydropyridine

There total 6 articles about 6-ethoxy-2,3,4,5-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

piperidin-2-one (675-20-7) + triethyloxonium fluoroborate (368-39-8) → 6-ethoxy-2,3,4,5-tetrahydro-pyridine (15200-13-2)

Guidance literature:

In dichloromethane; at 20 ℃;

Reference yield:

Cyclopentanone oxime (1192-28-5) → 6-ethoxy-2,3,4,5-tetrahydro-pyridine (15200-13-2)

Guidance literature:

With pyridine; benzenesulfonyl chloride; at -10 ℃; anschliessend mit wss.Schwefelsaeure und Erwaermen des Reaktionsprodukts in Chloroform mit Aethanol;

Reference yield:

cyclopentanone (120-92-3) → 6-ethoxy-2,3,4,5-tetrahydro-pyridine (15200-13-2)

Guidance literature:

With hydrogen azide; benzene; und anschliessend mit Aethanol und Chlorwasserstoff oder mit einem Gemisch von wss.Schwefelsaeure und Aethanol;

upstream raw materials:

piperidin-2-one

Cyclopentanone oxime

cyclopentanone

triethyloxonium fluoroborate

Downstream raw materials:

7,8,9-trihydropyrido[2,1-b]quinazolin-11(6H)-one

3-Oxo-3-phenyl-2-piperidin-(2E)-ylidene-propionic acid ethyl ester

2-{(E)-4-[2-Ethylamino-5-(4-nitro-phenyl)-thiazol-4-yl]-butylimino}-piperidine; hydrobromide

1-(2-Indol-3-ylethyl)piperidin-2-one

Refernces

• 1、 Beckmann, Udo,Eichberger, Eva,Lindner, Monika,Bongartz, Melanie,Kunz, Peter C.. "Modular routes towards new N,O-bidentate ligands containing an electronically delocalised β-enaminone chelating backbone". supporting information; experimental part. p. 4139 - 4147. Retrieved 2009/04/11.