2,4-DIMETHOXYPHENETHYLAMINE

Base Information

• Chemical Name: 2,4-DIMETHOXYPHENETHYLAMINE
• CAS No.: 15806-29-8
• Molecular Formula: C10H15NO2
• Molecular Weight: 181.235
• Hs Code.: 2922299090
• Mol file: 15806-29-8.mol

Synonyms:2,4-Dimethoxybenzeneethanamine;2,4-Dimethoxyphenethylamine;2-(2,4-Dimethoxyphenyl)ethanamine;2-(2,4-Dimethoxyphenyl)ethylamine;Phenethylamine,2,4-dimethoxy- (6CI,8CI);

Chemical Property of 2,4-DIMETHOXYPHENETHYLAMINE

Chemical Property:

• Vapor Pressure: 0.00664mmHg at 25°C
• Refractive Index: 1.522
• Boiling Point: 286 °C at 760 mmHg
• PKA: 9.74±0.10(Predicted)
• Flash Point: 137.8 °C
• PSA: 44.48000
• Density: 1.041 g/cm³
• LogP: 1.90530

Purity/Quality:

99% ^*data from raw suppliers

1-(2,4-dimethoxyphenyl)ethan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DIMETHOXYPHENETHYLAMINE

There total 9 articles about 2,4-DIMETHOXYPHENETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,4-dimethoxy-β-nitro-styrene (37630-19-6,1891-10-7) → 2,4-dimethoxyphenethylamine (15806-29-8)

Guidance literature:

With lithium borohydride; chloro-trimethyl-silane; In tetrahydrofuran; at 22 ℃; for 24h;

DOI:10.1002/hlca.19910740607

Reference yield: 55.0%

2-(2,4-dimethoxyphenyl)nitroethylene (108773-20-2) → 2,4-dimethoxyphenethylamine (15806-29-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 1.5h; Heating;

DOI:10.1021/jm00390a009

Reference yield:

2,4-Dimethoxybenzaldehyde (613-45-6) → 2,4-dimethoxyphenethylamine (15806-29-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / ammonium acetate / acetic acid / 2 h / Heating

2: 55 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 1.5 h / Heating

With ammonium acetate; lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; acetic acid;

DOI:10.1021/jm00390a009

upstream raw materials:

(2,4-dimethoxy-phenyl)-acetaldehyde-oxime

3-(2,4-dimethoxy-phenyl)-propionic acid amide

2,4-dimethoxy-β-nitro-styrene

2-(2,4-dimethoxyphenyl)nitroethylene

Downstream raw materials:

(2,4-dimethoxy-phenethyl)-urea

(2,4-dimethoxy-phenethyl)-methyl-amine

N-(2,4-dimethoxy-phenethyl)-benzamide

3-(3,4-dimethoxyphenethyl)-6-nitro-3H-imidazo[4,5-b]pyridine

Refernces

• 1、 Miessner, Merle,Crescenzi, Orlando,Napolitano, Alessandra,Prota, Giuseppe,Andersen, Svend Olav,Peter, Martin G.. "Biphenyltetrols and Dibenzofuranones from Oxidative Coupling of Resorcinols with 4-Alkylpyrocatechols: New Clues to the Mechanism of Insect Cuticle Sclerotization". . p. 1205 - 1212. Retrieved 2007/10/02.
• 2、 -. "7-(2-AMINOETHYL)-1,3-BENZTHIA- OR OXA-ZOL-2(3H)-ONES". . . Retrieved 2008/06/13.