Potassium p-toluate

Base Information

• Chemical Name: Potassium p-toluate
• CAS No.: 16518-25-5
• Molecular Formula: C8H8 O2 . K
• Molecular Weight: 174.241
• Hs Code.: 2916399090
• Mol file: 16518-25-5.mol

Synonyms:Benzoicacid, 4-methyl-, potassium salt (9CI); p-Toluic acid, potassium salt (8CI);4-Methylbenzoic acid potassium salt; Potassium p-methylbenzoate; Potassiump-toluate

Chemical Property of Potassium p-toluate

Chemical Property:

• PSA: 40.13000
• LogP: 0.35850

Purity/Quality:

99.90% ^*data from raw suppliers

Potassium 4-methylbenzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: p-Toluic Acid is the parent compound for Potassium 4-methylbenzoate. p-Toluic Acid (T536125) is used as a reagent in the synthesis of several organic compounds including that of 2-aryl-1,3,4-oxadiazole derivatives which are potential antibacterial agents. Also used in the synthesis of 4-(bromomethyl) benzoic acid.

Technology Process of Potassium p-toluate

There total 4 articles about Potassium p-toluate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-methyl-benzoic acid methyl ester (99-75-2) → potassium p-methyl benzoate (16518-25-5)

Guidance literature:

With Triton X-114; potassium thioacetate; at 150 ℃;

DOI:10.1016/j.tetlet.2005.11.048

Reference yield:

p-Toluic acid (99-94-5) → potassium p-methyl benzoate (16518-25-5)

Guidance literature:

With potassium tert-butylate; In ethanol; for 1h;

DOI:10.1002/anie.201208755

Reference yield:

4-Methylbenzyl alcohol (589-18-4) → potassium p-methyl benzoate (16518-25-5)

Guidance literature:

With chloro(η⁶-p-cymene)[2-(2,6-diisopropylphenyl)-5-(1,3-diisopropyl-2,4,6-trioxohexahydropyrimidin-5-yl-κC⁵)imidazo[1,5-a]pyridin-3-ylidene-κC³]ruthenium(II); potassium hydroxide; In dichloromethane; o-xylene; at 150 ℃; Schlenk technique;

DOI:10.1021/acs.organomet.1c00458

upstream raw materials:

4-methyl-benzoic acid methyl ester

p-Toluic acid

4-Methylbenzyl alcohol

Downstream raw materials:

bis(4-methylbenzoyloxy)methane

benzenesulfonic-p-methylbenzoic anhydride

4-methylbenzoic acid benzyl ester

methyl-2-deoxy-3,5-di-O-p-toluoyl-α-L-erythropentofuranoside

Refernces

• 1、 Abad Galán, Laura,Sobolev, Alexandre N.,Zysman-Colman, Eli,Ogden, Mark I.,Massi, Massimiliano. "Lanthanoid complexes supported by retro-Claisen condensation products of β-triketonates". supporting information. p. 17469 - 17478. Retrieved 2019/01/03.
• 2、 Bhadra, Sukalyan,Dzik, Wojciech I.,Goo?en, Lukas J.. "Synthesis of aryl ethers from benzoates through carboxylate-directed C-H-activating alkoxylation with concomitant protodecarboxylation". supporting information. p. 2959 - 2962. Retrieved 2013/04/10.