TETRAETHYL(1,4-BUTYLENE)BISPHOSPHONATE

Base Information

• Chemical Name: TETRAETHYL(1,4-BUTYLENE)BISPHOSPHONATE
• CAS No.: 7203-67-0
• Molecular Formula: C₁₂H₂₈O₆P₂
• Molecular Weight: 330.298
• Hs Code.: 29310099
• Mol file: 7203-67-0.mol

Synonyms:Phosphonicacid, tetramethylenedi-, tetraethyl ester (6CI,7CI,8CI);1,4-Bis(diethoxyphosphinyl)butane;Tetraethyl 1,4-butanediyldiphosphonic acid;Tetraethyl butane-1,4-diphosphonate;

Chemical Property of TETRAETHYL(1,4-BUTYLENE)BISPHOSPHONATE

Chemical Property:

• Vapor Pressure: 9.64E-07mmHg at 25°C
• Refractive Index: 1.4465-1.4485
• Boiling Point: 415.8 °C at 760 mmHg
• Flash Point: 218.7 °C
• PSA: 90.68000
• Density: 1.099 g/cm³
• LogP: 4.29880

Purity/Quality:

99% ^*data from raw suppliers

Tetraethyl(1,4-butylene)bisphosphonate 94% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of TETRAETHYL(1,4-BUTYLENE)BISPHOSPHONATE

There total 5 articles about TETRAETHYL(1,4-BUTYLENE)BISPHOSPHONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,4-dibromo-butane (110-52-1) + triethyl phosphite (122-52-1) → 1,4-bis(diethoxyphosphinyl)butane (7203-67-0)

Guidance literature:

at 160 ℃;

DOI:10.1080/00397919808004465

Reference yield:

Diethyl vinylphosphonate (682-30-4) → 1,4-bis(diethoxyphosphinyl)butane (7203-67-0)

Guidance literature:

With tetraethylammonium tosylate; In methanol; water; (electrolysis);

DOI:10.1021/jo01020a063

Reference yield:

1,4-dibromo-butane (110-52-1) + sodium diethyl phosphite (2303-76-6,118080-94-7) → 1,4-bis(diethoxyphosphinyl)butane (7203-67-0)

Guidance literature:

With diethyl ether;

DOI:10.1007/BF00899234

upstream raw materials:

1,4-dibromo-butane

sodium diethyl phosphite

triethyl phosphite

Diethyl vinylphosphonate

Downstream raw materials:

1,4-butylenediphosphonic acid

Refernces

• 1、 Crisenza, Giacomo E. M.,McCreanor, Niall G.,Bower, John F.. "Branch-selective, Iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy". supporting information. p. 10258 - 10261. Retrieved 2014/08/05.
• 2、 Griffith, Julie A.,McCauley, David J.,Barrans Jr., Richard E.,Herlinger, Albert W.. "High yield synthesis of tetraethyl alkylenediphosphonates via the Michaelis-Arbuzov reaction". . p. 4317 - 4323. Retrieved 2007/10/03.