(8-Iodonaphthalen-1-yl)methanol

Base Information

• Chemical Name: (8-Iodonaphthalen-1-yl)methanol
• CAS No.: 85864-84-2
• Molecular Formula: C11H9IO
• Molecular Weight: 284.096
• Hs Code.: 2906299090
• DSSTox Substance ID: DTXSID90381618
• Wikidata: Q82172542
• Mol file: 85864-84-2.mol

Synonyms:(8-Iodo-1-Naphthyl)Methanol;85864-84-2;(8-iodonaphthalen-1-yl)methanol;1-Naphthalenemethanol,8-iodo-;CDS1_000765;Maybridge1_005517;8-Iodonaphthalene-1-methanol;DivK1c_001805;HMS557C17;DTXSID90381618;MFCD00099244;AKOS002838715;FT-0604851

Chemical Property of (8-Iodonaphthalen-1-yl)methanol

Chemical Property:

• Vapor Pressure: 5.24E-07mmHg at 25°C
• Refractive Index: 1.727
• Boiling Point: 396.8 °C at 760 mmHg
• Flash Point: 193.8 °C
• PSA: 20.23000
• Density: 1.781 g/cm³
• LogP: 2.93670
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 283.96981
• Heavy Atom Count: 13
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

(8-Iodo-1-naphthyl)methanol 95% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)CO)C(=CC=C2)I

Technology Process of (8-Iodonaphthalen-1-yl)methanol

There total 1 articles about (8-Iodonaphthalen-1-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) → (8-iodonaphthalen-1-yl)methanol (85864-84-2)

Guidance literature:

With diisobutylaluminium hydride; In diethyl ether; hexane; at -40 ℃; for 0.5h;

DOI:10.1021/ja00357a021

Reference yield: 88.0%

benzyl bromide (100-39-0) + (8-iodonaphthalen-1-yl)methanol (85864-84-2) → 1-(benzyloxymethyl)-8-iodonaphthalene (1037295-13-8)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2008.01.144

Reference yield: 73.0%

(8-iodonaphthalen-1-yl)methanol (85864-84-2) → 1-naphthaldehyde (66-77-3)

Guidance literature:

With cesium pivalate; bis-diphenylphosphinomethane; palladium diacetate; In N,N-dimethyl-formamide; at 120 ℃; for 2h;

DOI:10.1016/j.tet.2008.01.144

upstream raw materials:

diazomethane

Downstream raw materials:

8-iodonaphthalene-1-carbaldehyde

8-iodo-1-naphthaldehyde p-tosylhydrazone

3H-benzindazole

1-(benzyloxymethyl)-8-iodonaphthalene

Refernces