N-Isopropylpropylamine

Base Information

• Chemical Name: N-Isopropylpropylamine
• CAS No.: 21968-17-2
• Molecular Formula: C6H15N
• Molecular Weight: 101.192
• Hs Code.: 2921199090
• European Community (EC) Number: 244-688-2
• UNII: K1P2FY26RO
• DSSTox Substance ID: DTXSID20176377
• Nikkaji Number: J225.495F
• Wikidata: Q27281826
• Mol file: 21968-17-2.mol

Synonyms:N-Isopropylpropylamine;21968-17-2;N-propan-2-ylpropan-1-amine;(propan-2-yl)(propyl)amine;N-Isopropyl-n-propylamine;1-Propanamine, N-(1-methylethyl)-;K1P2FY26RO;MFCD00027095;N-isopropylpropan-1-amine;propyl-isopropylamine;N-Isopropyl-propylamine;n-n-propylisopropylamine;PROPYLISOPROPYLAMINE;UNII-K1P2FY26RO;N-Isopropylpropane-1-amine;N-Isopropyl-n-propylamine #;SCHEMBL58831;n-isopropyl-n-(n-propyl)amine;DTXSID20176377;PROPYLAMINE, N-ISOPROPYL-;N-(1-methylethyl)-1-propylamine;EINECS 244-688-2;AKOS000159966;N-Isopropyl-N-propylamine, AldrichCPR;BS-42311;FT-0638170;EN300-40194;F87476;Q27281826;F8889-6089;Z138446224

Chemical Property of N-Isopropylpropylamine

Chemical Property:

• Vapor Pressure: 32.9mmHg at 25°C
• Melting Point: -87.87°C (estimate)
• Refractive Index: 1.403
• Boiling Point: 102.9 °C at 760 mmHg
• PKA: 10.76±0.28(Predicted)
• Flash Point: 1.1 °C
• PSA: 12.03000
• Density: 0.739 g/cm³
• LogP: 1.78530
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 101.120449483
• Heavy Atom Count: 7
• Complexity: 33.2

Purity/Quality:

99% ^*data from raw suppliers

N-Isopropylpropylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C,Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCNC(C)C
• Uses: N-Isopropylpropylamine is used as an active pharmaceutical ingredients.

Technology Process of N-Isopropylpropylamine

There total 7 articles about N-Isopropylpropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propyl bromide (106-94-5) + isopropylamine (75-31-0) → N-isopropyl-n-propylamine (21968-17-2)

Guidance literature:

DOI:10.1007/BF00903144

Reference yield:

N-(isopropylidene)allylamine (30533-01-8) → N-isopropyl-n-propylamine (21968-17-2)

Guidance literature:

With nickel; at 100 - 150 ℃; under 11032.6 - 51485.6 Torr; Hydrogenation;

DOI:10.1021/jo01372a010

Reference yield:

propylamine (107-10-8,42939-71-9) + acetone (67-64-1) → N-isopropyl-n-propylamine (21968-17-2)

Guidance literature:

With carbon monoxide; acetic acid; at 160 ℃; under 147102 Torr;

upstream raw materials:

N-(isopropylidene)allylamine

propylamine

acetone

propyl bromide

Downstream raw materials:

N-n-propyl-N-isopropyl 2-phenylacetamide

Refernces

• 1、 Smirnov, Yu. D.,Tomilov, A. P.. "ELECTROCHEMICAL REDUCTIVE AMINATION. I. AMINATION OF ALIPHATIC KETONES BY PRIMARY AMINES". . p. 42 - 48. Retrieved 2007/10/02.
• 2、 Cristau, Henri-Jean,Garcia, Chantal,Kadoura, Jumah,Torreilles, Eliane. "PHOSPHONIUM DIAZA-DIYLIDS AND AZA-YLDIID AS NEW AND EFFICIENT REAGENTS FOR PRIMARY AND SECONDARY AMINES SYNTHESIS". . p. 151 - 154. Retrieved 2007/10/02.