4-Bromo-2-nitrophenylhydrazine

Base Information

• Chemical Name: 4-Bromo-2-nitrophenylhydrazine
• CAS No.: 59488-34-5
• Molecular Formula: C6H6BrN3O2
• Molecular Weight: 232.037
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID50420678
• Wikidata: Q82231988
• Mol file: 59488-34-5.mol

Synonyms:4-Bromo-2-nitrophenylhydrazine;59488-34-5;(4-bromo-2-nitrophenyl)hydrazine;SCHEMBL16126356;DTXSID50420678;MFCD03788274;AKOS000190966;PS-5489;CS-0160812;FT-0640606;E84025;A832338

Chemical Property of 4-Bromo-2-nitrophenylhydrazine

Chemical Property:

• Vapor Pressure: 0.000111mmHg at 25°C
• Refractive Index: 1.719
• Boiling Point: 336.6 °C at 760 mmHg
• PKA: 3.34±0.27(Predicted)
• Flash Point: 157.4 °C
• PSA: 83.87000
• Density: 1.869 g/cm³
• LogP: 2.93940
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 230.96434
• Heavy Atom Count: 12
• Complexity: 173

Purity/Quality:

98%Min ^*data from raw suppliers

4-Bromo-2-nitrophenylhydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 5-11-20/21/22
• Safety Statements: 15-22-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Br)[N+](=O)[O-])NN

Technology Process of 4-Bromo-2-nitrophenylhydrazine

There total 2 articles about 4-Bromo-2-nitrophenylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Bromo-1-fluoro-2-nitrobenzene (364-73-8) → (4-bromo-2-nitrophenyl)hydrazine (59488-34-5)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; Cooling with ice;

Reference yield:

4-Bromo-2-nitroaniline (875-51-4) → (4-bromo-2-nitrophenyl)hydrazine (59488-34-5)

Guidance literature:

With hydrogenchloride; sodium nitrite; man reduziert die Diazoverbindung mit Zinnchloruer und Salzsaeure; das ausgeschiedene Zinndoppelsalz zersetzt man in waessr. Loesung mit Schwefelwasserstoff;

Reference yield: 83.0%

(4-bromo-2-nitrophenyl)hydrazine (59488-34-5) + ethyl 3-oxo-3-phenylpropionate (94-02-0) → 3-[(4-Bromo-2-nitro-phenyl)-hydrazono]-3-phenyl-propionic acid ethyl ester (94724-85-3)

Guidance literature:

With perchloric acid; In ethanol; for 1h;

upstream raw materials:

4-Bromo-2-nitroaniline

4-Bromo-1-fluoro-2-nitrobenzene

Downstream raw materials:

(Z)-3-[N'-(4-Bromo-2-nitro-phenyl)-hydrazinocarbonyl]-acrylic acid

C₁₃H₁₆BrN₃O₅

3-[(4-Bromo-2-nitro-phenyl)-hydrazono]-butyric acid ethyl ester

3-[(4-Bromo-2-nitro-phenyl)-hydrazono]-3-phenyl-propionic acid ethyl ester

Refernces