Technology Process of 19-bromononadecanoic Acid
There total 6 articles about 19-bromononadecanoic Acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: methanol; toluene-4-sulfonic acid / dichloromethane
2: sulfuric acid; water; hydrogen bromide / 110 °C
With
methanol; sulfuric acid; water; hydrogen bromide; toluene-4-sulfonic acid;
In
dichloromethane;
DOI:10.1016/j.tetlet.2011.11.021
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogen bromide / water; toluene / Reflux
2: toluene-4-sulfonic acid / dichloromethane
3: [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; lithium bromide / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 20 h / 20 °C
4: methanol; toluene-4-sulfonic acid / dichloromethane
5: sulfuric acid; water; hydrogen bromide / 110 °C
With
methanol; [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(ll) dichloride; sulfuric acid; water; hydrogen bromide; toluene-4-sulfonic acid; lithium bromide;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; dichloromethane; water; toluene;
3: Negishi coupling reaction;
DOI:10.1016/j.tetlet.2011.11.021