2-amino-6-methylphenylacetaldehyde ethylene acetal

Base Information

• Chemical Name: 2-amino-6-methylphenylacetaldehyde ethylene acetal
• CAS No.: 107469-25-0
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.246
• Mol file: 107469-25-0.mol

Synonyms:2-amino-6-methylphenylacetaldehyde ethylene acetal

Chemical Property of 2-amino-6-methylphenylacetaldehyde ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-6-methylphenylacetaldehyde ethylene acetal

There total 4 articles about 2-amino-6-methylphenylacetaldehyde ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-methyl-6-nitrophenylacetaldehyde ethylene acetal (107469-24-9) → 2-amino-6-methylphenylacetaldehyde ethylene acetal (107469-25-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; Ambient temperature;

Reference yield:

2-bromo-3-nitrotoluene (41085-43-2) → 2-amino-6-methylphenylacetaldehyde ethylene acetal (107469-25-0)

Guidance literature:

Multi-step reaction with 4 steps

1: Pd(PPh₃)2Cl₂, CuI / triethylamine / 24 h / Heating

2: ethanol / 6 h / Heating

3: 85 percent / conc. HCl / 2 h / 60 °C

4: 90 percent / H₂ / 5 percent Pd-C / methanol / Ambient temperature

With hydrogenchloride; hydrogen; bis-triphenylphosphine-palladium(II) chloride; palladium on activated charcoal; copper(l) iodide; In methanol; ethanol; triethylamine;

Reference yield:

2-(2-ethoxyethenyl)-3-methylnitrobenzene (107469-23-8) → 2-amino-6-methylphenylacetaldehyde ethylene acetal (107469-25-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / conc. HCl / 2 h / 60 °C

2: 90 percent / H₂ / 5 percent Pd-C / methanol / Ambient temperature

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol;

upstream raw materials:

2-methyl-6-nitrophenylacetaldehyde ethylene acetal

2-bromo-3-nitrotoluene

2-(2-ethoxyethenyl)-3-methylnitrobenzene

6-methyl-2-nitro-1-[2-(trimethylsilyl)ethynyl]-benzene

Downstream raw materials:

4-methyl-1H-indole

Refernces