H-BETA-ALA-PNA HBR

Base Information

• Chemical Name: H-BETA-ALA-PNA HBR
• CAS No.: 111196-17-9
• Molecular Formula: C9H11 N3 O3 . Br H
• Molecular Weight: 290.117
• Mol file: 111196-17-9.mol

Synonyms:Propanamide,3-amino-N-(4-nitrophenyl)-, monohydrobromide (9CI)

Chemical Property of H-BETA-ALA-PNA HBR

Chemical Property:

• PSA: 100.94000
• LogP: 3.13670

Purity/Quality:

98.5% ^*data from raw suppliers

H-β-Ala-pNA HBr ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: H-beta-Ala-pNA HBr is a chromogenic substrate.

Technology Process of H-BETA-ALA-PNA HBR

There total 2 articles about H-BETA-ALA-PNA HBR which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyloxycarbonyl-β-alanine p-nitroanilide (111196-15-7) → β-alanine p-nitroanilide hydrobromide (111196-17-9)

Guidance literature:

With hydrogen bromide; In acetic acid; for 0.166667h;

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → β-alanine p-nitroanilide hydrobromide (111196-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) PCl₃ / 1) pyridine, -20 deg C, 30 min., then 30 min., room temp.; 2) reflux, 3 h

2: 36percent HBr / acetic acid / 0.17 h

With hydrogen bromide; phosphorus trichloride; In acetic acid;

Reference yield:

β-alanine p-nitroanilide hydrobromide (111196-17-9) + L-histidine (71-00-1,26062-48-6,90081-11-1) → carnosine (305-84-0)

Guidance literature:

With recombinant β-aminopeptidase BapA from Sphingosinicella xenopeptidilytica 3-2W4; at 37 ℃; pH=10; Reagent/catalyst; pH-value; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1002/adsc.200900697

upstream raw materials:

benzyloxycarbonyl-β-alanine p-nitroanilide

4-nitro-aniline

Downstream raw materials:

carnosine

Refernces