3-(2,6,6-Trimethyl-1-cyclohexene-1-yl)allyl alcohol

Base Information

• Chemical Name: 3-(2,6,6-Trimethyl-1-cyclohexene-1-yl)allyl alcohol
• CAS No.: 4808-01-9
• Molecular Formula: C₁₂H₂₀O
• Molecular Weight: 180.29
• Mol file: 4808-01-9.mol

Synonyms:3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-ol

Chemical Property of 3-(2,6,6-Trimethyl-1-cyclohexene-1-yl)allyl alcohol

Chemical Property:

• Boiling Point: 78-80 °C(Press: 0.3 Torr)
• PKA: 14.61±0.10(Predicted)
• Density: 0.961±0.06 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2,6,6-Trimethyl-1-cyclohexene-1-yl)allyl alcohol

There total 5 articles about 3-(2,6,6-Trimethyl-1-cyclohexene-1-yl)allyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

3-(2,6,6-timethylcyclohex-1-enyl)propenoic acid (4951-39-7) → 3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-ol (4808-01-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 2h;

Reference yield:

4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one (79-77-6,14901-07-6) → 3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-ol (4808-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; bromine / water; 1,4-dioxane / 6 h / 0 - 20 °C

2: lithium aluminium tetrahydride / diethyl ether / 2 h / 0 °C

With lithium aluminium tetrahydride; bromine; sodium hydroxide; In 1,4-dioxane; diethyl ether; water;

Reference yield:

3-Methyl-1-(2,6,6-trimethyl-cyclohexen-(1)-yl)-pentadien-(1,3)-saeure-(5)-nitril (19834-52-7) → 3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-ol (4808-01-9)

Guidance literature:

Multi-step reaction with 4 steps

1: diisobutylaluminium hydride / toluene / 1 h / -5 - 0 °C

2: dipyridinium dichromate / dichloromethane / 4 h / 0 °C

3: sodium hydroxide; bromine / water; 1,4-dioxane / 6 h / 0 - 20 °C

4: lithium aluminium tetrahydride / diethyl ether / 2 h / 0 °C

With lithium aluminium tetrahydride; dipyridinium dichromate; bromine; diisobutylaluminium hydride; sodium hydroxide; In 1,4-dioxane; diethyl ether; dichloromethane; water; toluene;

upstream raw materials:

4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one

3-Methyl-1-(2,6,6-trimethyl-cyclohexen-⁽¹⁾-yl)-pentadien-(1,3)-saeure-⁽⁵⁾-nitril

3-methyl-5-(2,6,6-trimethylcyclohex-1-enyl)penta-2, 4-dienal

3-(2,6,6-timethylcyclohex-1-enyl)propenoic acid

Downstream raw materials:

3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propenal

Refernces