2-[1,1'-BIPHENYL]-4-YL-5,8-DIMETHOXYQUINOLINE

Base Information

• Chemical Name: 2-[1,1'-BIPHENYL]-4-YL-5,8-DIMETHOXYQUINOLINE
• CAS No.: 860783-99-9
• Molecular Formula: C₂₃H₁₉NO₂
• Molecular Weight: 341.409
• Mol file: 860783-99-9.mol

Synonyms:2-(4-biphenyl)-5,8-dimethoxyquinoline

Chemical Property of 2-[1,1'-BIPHENYL]-4-YL-5,8-DIMETHOXYQUINOLINE

Chemical Property:

• Melting Point: 162-162.5 °C
• Boiling Point: 551.6±45.0 °C(Predicted)
• PKA: 2.12±0.32(Predicted)
• Density: 1.155±0.06 g/cm3(Predicted)

Purity/Quality:

2-[1,1'-BIPHENYL]-4-YL-5,8-DIMETHOXYQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[1,1'-BIPHENYL]-4-YL-5,8-DIMETHOXYQUINOLINE

There total 1 articles about 2-[1,1'-BIPHENYL]-4-YL-5,8-DIMETHOXYQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

biphenyl-4-acetaldehyde (92-91-1) + 2-amino-3,6-dimethoxylbenzaldehyde (126522-16-5) → 2-(4-biphenyl)-5,8-dimethoxyquinoline (860783-99-9)

Guidance literature:

With potassium hydroxide; In ethanol; for 20h; Heating;

DOI:10.1021/jm7014099

Reference yield:

2-(4-biphenyl)-5,8-dimethoxyquinoline (860783-99-9) → 2-(4-biphenyl)-quinoline-5,8-dione (1021355-04-3)

Guidance literature:

With ammonium cerium(IV) nitrate; In water; acetonitrile; for 0.666667h;

DOI:10.1021/jm7014099

upstream raw materials:

biphenyl-4-acetaldehyde

2-amino-3,6-dimethoxylbenzaldehyde

Downstream raw materials:

2-(4-biphenyl)-quinoline-5,8-dione

Refernces