5-Pyrimidinemethanamine, 4-amino- (9CI)

Base Information

• Chemical Name: 5-Pyrimidinemethanamine, 4-amino- (9CI)
• CAS No.: 103694-27-5
• Molecular Formula: C₅H₈N₄
• Molecular Weight: 124.145
• Hs Code.: 2933599090
• Mol file: 103694-27-5.mol

Synonyms:Pyrimidine,4-amino-5-(aminomethyl)- (6CI); 4-Amino-5-(aminomethyl)pyrimidine;4-Amino-5-pyrimidinemethylamine; [(4-Aminopyrimidin-5-yl)methyl]amine

Chemical Property of 5-Pyrimidinemethanamine, 4-amino- (9CI)

Chemical Property:

• PSA: 78.55000
• LogP: 0.14790
• Storage Temp.: 2-8°C
• Solubility.: DMF, DMSO, Methanol

Purity/Quality:

99.90% ^*data from raw suppliers

4-Amino-5-pyrimidinemethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Amino-5-pyrimidinemethylamine is a substituted pyrimidine and an intermediate in the synthesis of Thiamine (T344185) analogues.

Technology Process of 5-Pyrimidinemethanamine, 4-amino- (9CI)

There total 3 articles about 5-Pyrimidinemethanamine, 4-amino- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-((4-aminopyrimidin-5-yl)methyl)formamide (1196-75-4) → 4-Amino-5-aminomethyl-pyrimidin (103694-27-5)

Guidance literature:

With sodium hydroxide; at 75 ℃; for 3h;

DOI:10.1021/op300190s

Reference yield:

4-amino-5-cyanopyrimidine (16357-69-0) → 4-Amino-5-aminomethyl-pyrimidin (103694-27-5)

Guidance literature:

With methanol; ammonia; nickel; Hydrogenation;

DOI:10.1002/hlca.19500330612

Reference yield:

→ 4-Amino-5-aminomethyl-pyrimidin (103694-27-5)

Guidance literature:

4-Amino-5-formaminomethyl-pyrimidin, 10percentig.HCl <70grad>;

upstream raw materials:

4-amino-5-cyanopyrimidine

N-((4-aminopyrimidin-5-yl)methyl)formamide

Downstream raw materials:

3,4-dihydro-1H-pyrimido[4,5-d]pyrimidine-2-thione

Refernces