2-chloro-4-acetamidoacetophenone

Base Information

• Chemical Name: 2-chloro-4-acetamidoacetophenone
• CAS No.: 103273-72-9
• Molecular Formula: C10H10ClNO2
• Molecular Weight: 211.648
• Mol file: 103273-72-9.mol

Synonyms:Acetanilide,4'-acetyl-3'-chloro-(6CI);

Chemical Property of 2-chloro-4-acetamidoacetophenone

Chemical Property:

• Melting Point: 109-110 °C(Solv: water (7732-18-5))
• Boiling Point: 382.9 °C at 760 mmHg
• PKA: 13.92±0.70(Predicted)
• Flash Point: 185.4 °C
• PSA: 46.17000
• Density: 1.274 g/cm³
• LogP: 2.57400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloro-4-acetamidoacetophenone

There total 1 articles about 2-chloro-4-acetamidoacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Chloroacetanilide (588-07-8) + acetyl chloride (75-36-5) → acetic acid-(4-acetyl-3-chloro-anilide) (103273-72-9)

Guidance literature:

With aluminium trichloride;

Reference yield:

acetic acid-(4-acetyl-3-chloro-anilide) (103273-72-9) → 4-Acetylamino-2-chlorobenzoic acid (38667-55-9)

Guidance literature:

With potassium permanganate; water; magnesium sulfate;

Reference yield:

acetic acid-(4-acetyl-3-chloro-anilide) (103273-72-9) → 4-amino-2-chloroacetophenone (72531-23-8)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

3-Chloroacetanilide

acetyl chloride

Downstream raw materials:

4-Acetylamino-2-chlorobenzoic acid

4-amino-2-chloroacetophenone