2,6-Dichloro-4-(chloromethyl)pyridine

Base Information

• Chemical Name: 2,6-Dichloro-4-(chloromethyl)pyridine
• CAS No.: 101990-72-1
• Molecular Formula: C6H4Cl3N
• Molecular Weight: 196.46
• Hs Code.: 2933399090
• European Community (EC) Number: 695-384-5
• DSSTox Substance ID: DTXSID70383271
• Wikidata: Q82174937
• Mol file: 101990-72-1.mol

Synonyms:2,6-dichloro-4-(chloromethyl)pyridine;101990-72-1;Pyridine, 2,6-dichloro-4-(chloromethyl)-;2,6-dichloro-4-chloromethyl-pyridine;2,6-dichloro-isonicotinyl chloride;SCHEMBL190086;DTXSID70383271;UYBVOPLURVHJOX-UHFFFAOYSA-N;BEA99072;2,6-dichloro-4-chloromethylpyridine;MFCD03783562;AKOS006238774;AB15881;CG-0737;FT-0610571;EN300-52072;2,6-dichloro-4-(chloromethyl)pyridine, AldrichCPR;J-000531

Chemical Property of 2,6-Dichloro-4-(chloromethyl)pyridine

Chemical Property:

• Vapor Pressure: 0.0043mmHg at 25°C
• Refractive Index: 1.567
• Boiling Point: 287.4 °C at 760 mmHg
• Flash Point: 155 °C
• PSA: 12.89000
• Density: 1.463 g/cm³
• LogP: 3.12720
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 194.940932
• Heavy Atom Count: 10
• Complexity: 99.2

Purity/Quality:

98%min ^*data from raw suppliers

2,6-Dichloro-4-(chloromethyl)pyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:Harmful if swallowed.; R34:Causes burns.
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C=C(N=C1Cl)Cl)CCl
• Use Description: 2,6-Dichloro-4-(chloromethyl)pyridine is a chemical compound with several applications in different fields. In the field of agrochemicals and pesticides, it serves as a key intermediate in the synthesis of various herbicides and insecticides, contributing to the protection of crops from pests and weeds. Its role is pivotal in the development of effective agricultural chemicals that help improve crop yield and quality. In addition, in the pharmaceutical and chemical industries, this compound can be used as a building block for the synthesis of complex organic molecules, potentially leading to the discovery of new drugs or specialty chemicals. Furthermore, in academic research and chemical analysis, it may serve as a reference compound for the study of pyridine derivatives and organic reactions, aiding in the advancement of organic chemistry knowledge. Its versatile applications underscore its significance in advancing agriculture, chemistry, and scientific research, where it plays a crucial role in crop protection, chemical synthesis, and academic investigation.

Technology Process of 2,6-Dichloro-4-(chloromethyl)pyridine

There total 1 articles about 2,6-Dichloro-4-(chloromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,6-dichloropyridin-4-yl)methanol (101990-69-6) → 2,6-dichloro-pyridin-4-ylmethyl chloride (101990-72-1)

Guidance literature:

With pyridine; thionyl chloride; sodium sulfate; In diethyl ether; water; toluene;

Reference yield:

2,6-dichloro-pyridin-4-ylmethyl chloride (101990-72-1) + 5,5-dimethyl-3-{4-[(trifluoromethyl)-thio]phenyl}imidazolidine-2,4-dione (89020-94-0) → 1-(2,6-dichloropyrid-4-ylmethyl)-5,5-dimethyl-3-(4-trifluoromethylsulfanylphenyl)imidazolidine-2,4-dione

Guidance literature:

With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 80 ℃; for 6h;

Reference yield:

2,6-dichloro-pyridin-4-ylmethyl chloride (101990-72-1) + C25H34N4O4 (1041399-27-2) → C31H37Cl2N5O4 (1041399-84-1)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide;

upstream raw materials:

(2,6-dichloropyridin-4-yl)methanol

Downstream raw materials:

2,6-dichloroisonicotinic acid ethyl ester

2,6-dichloropyridine-4-carboxamide

C₃₁H₃₇Cl₂N₅O₄

Refernces