cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride

Base Information

• Chemical Name: cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride
• CAS No.: 18414-30-7
• Molecular Formula: C₆H₁₁NO₂*ClH
• Molecular Weight: 165.62
• Hs Code.: 2922498590
• European Community (EC) Number: 624-344-1
• DSSTox Substance ID: DTXSID80926072
• ChEMBL ID: CHEMBL542974
• Mol file: 18414-30-7.mol

Synonyms:128110-37-2;18414-30-7;(1R,2S)-2-aminocyclopentane-1-carboxylic Acid Hydrochloride;cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride;(1R,2S)-(-)-2-Amino-1-cyclopentanecarboxylic acid hydrochloride;(1R,2S)-2-Aminocyclopentanecarboxylic Acid Hydrochloride;(1R,2S)-rel-2-Aminocyclopentanecarboxylic acid hydrochloride;cis-2-Aminocyclopentanecarboxylic acid hydrochloride;cis-2-Amino-cyclopentanecarboxylic acid hydrochloride;MFCD02181204;(1R,2S)-2-aminocyclopentane-1-carboxylic acid;hydrochloride;(1R,2S)-2-aminocyclopentanecarboxylic acid hcl;(1R,2S)-Cispentacin Hydrochloride;cis-|A-Cycloleucine hydrochloride;212755-84-5;(1R,2S)-2-Amino-cyclopentanecarboxylic acid hydrochloride;CIS-2-AMINO-1-CYCLOPENTANECARBOXYLIC AC&;CHEMBL542974;SCHEMBL3413778;DTXSID80926072;cis-beta-Cycloleucine hydrochloride;Cyclopentanecarboxylic acid, 2-amino-, hydrochloride, (1R,2S)-;MFCD05863555;MFCD16613996;AKOS015892971;AT13968;TS-7063;AC-26769;cis-2-Aminocyclopentanecarboxylic acid HCl;cis-2-Amino-cyclopentanecarboxylic acid HCl;A4074;CS-0035054;CS-0132060;EN300-211995;J-011798;J-500314;J-500404;(1R,2S)-2-AminocyclopentanecarboxylicAcidHydrochloride;Z2327569946;(1R,2S)-2-Amino-cyclopetanecarboxylic?acid?hydrochloride?salt;(1R,2S)-cis-2-Amino-cyclopentanecarboxylic acid hydrochloride;2-Aminocyclopentane-1-carboxylic acid--hydrogen chloride (1/1);cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride, >=95.0% (AT)

Chemical Property of cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride

Chemical Property:

• Appearance/Colour: solid
• Boiling Point: 264.7 °C at 760 mmHg
• Flash Point: 113.9 °C
• PSA: 63.32000
• LogP: 1.70070
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 165.0556563
• Heavy Atom Count: 10
• Complexity: 124

Purity/Quality:

99% ^*data from raw suppliers

cis-2-Aminocyclopentanecarboxylic acid hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C(C1)N)C(=O)O.Cl
• Isomeric SMILES: C1C[C@H]([C@H](C1)N)C(=O)O.Cl

Technology Process of cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride

There total 42 articles about cis-2-Amino-1-cyclopentanecarboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-Methyl-propane-2-sulfinic acid ((1S,2S)-2-cyano-cyclopentyl)-amide → (1S,2S)-2-aminocyclopentanecarboxylic acid hydrochloride (128052-92-6,158414-44-9,359849-58-4,18414-30-7)

Guidance literature:

With hydrogenchloride; at 75 ℃; for 19h;

DOI:10.1021/ol048458j

Reference yield: 84.0%

(-)-cispentacin (122672-46-2,37910-65-9) → (+)-(1S,2R)-2-aminocyclopentane-1-carboxylic acid hydrochloride (128052-92-6,158414-44-9,359849-58-4,18414-30-7)

Guidance literature:

With hydrogenchloride; In water; for 3h; Heating;

DOI:10.1021/ol034096o

Reference yield: 83.0%

cis-2-aza-3-oxobicyclo<3.2.0>heptane (22031-52-3,39155-94-7,39155-95-8,83151-31-9) → (±)-cis-2-aminocyclopentane-1-carboxylic acid hydrochloride (128052-92-6,158414-44-9,359849-58-4,18414-30-7)

Guidance literature:

With hydrogenchloride; In water; at 0 - 20 ℃; for 14h;

DOI:10.1021/op010204f

upstream raw materials:

cis-2-aza-3-oxobicyclo<3.2.0>heptane

isocyanate de chlorosulfonyle

cyclopentene

tert-butyl (1R,2R,αR)-2-(N-benzyl-N-α-methylbenzylamino)cyclopentanecarboxylate

Refernces

• 1、 Forró, Enik?,Galla, Zsolt,Fül?p, Ferenc. "The N-Hydroxymethyl Group as a Traceless Activating Group for the CAL-B-Catalysed Ring Cleavage of β-Lactams: A Type of Two-Step Cascade Reaction". . p. 2647 - 2652. Retrieved 2016/06/09.
• 2、 -. "New compounds". Page/Page column 9. . Retrieved 2009/07/10.