6-Thioguanosine diphosphate

Base Information

• Chemical Name: 6-Thioguanosine diphosphate
• CAS No.: 16541-19-8
• Molecular Formula: C₁₀H₁₅N₅O₁₀P₂S
• Molecular Weight: 459.27
• UNII: TDS82YCU9L
• Nikkaji Number: J630.359E
• Wikidata: Q76728107
• ChEMBL ID: CHEMBL3638284
• Mol file: 16541-19-8.mol

Synonyms:6-thioguanosine 5'-diphosphate;9-beta-ribofuranosyl-2-amino-6-mercaptopurine 5'-diphosphate;guanosine 5'-(beta-thio)diphosphate;p(S)pg;thioGDP

Chemical Property of 6-Thioguanosine diphosphate

Chemical Property:

• Boiling Point: 945°Cat760mmHg
• Flash Point: 525.3°C
• PSA: 287.21000
• Density: 2.55g/cm³
• LogP: -0.50220
• XLogP3: -3.9
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 6
• Exact Mass: 459.00148686
• Heavy Atom Count: 28
• Complexity: 765

Purity/Quality:

97% ^*data from raw suppliers

ThioguanosineDiphosphate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)NC(=NC2=S)N
• Isomeric SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)NC(=NC2=S)N

Technology Process of 6-Thioguanosine diphosphate

There total 1 articles about 6-Thioguanosine diphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

guanosine-5'-diphosphate (146-91-8) → 6-TGDP (16541-19-8)

Guidance literature:

With L-Cysteine; pyridoxal 5'-phosphate; YcfA adenylating enzyme from Escherichia coli; YcfC sulfur mobilizing enzyme from Escherichia coli; ATP; In aq. buffer; at 30 ℃; for 2h; pH=7.5;

DOI:10.1002/anie.201804158

upstream raw materials:

guanosine-5'-diphosphate

Refernces