2-Methoxi-5-methylphenylazid

Base Information

• Chemical Name: 2-Methoxi-5-methylphenylazid
• CAS No.: 77721-47-2
• Molecular Formula: C₈H₉N₃O
• Molecular Weight: 163.179
• Mol file: 77721-47-2.mol

Synonyms:2-Methoxi-5-methylphenylazid

Chemical Property of 2-Methoxi-5-methylphenylazid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methoxi-5-methylphenylazid

There total 1 articles about 2-Methoxi-5-methylphenylazid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-methylanizole (104-93-8) → 2-Methoxi-5-methylphenylazid (77721-47-2)

Guidance literature:

With trimethylsilylazide; bis-[(trifluoroacetoxy)iodo]benzene; Yield given. Multistep reaction; 1.) (CF₃)2CHOH, r. t.;

DOI:10.1016/S0040-4039(00)92160-9

Reference yield: 100.0%

2-Methoxi-5-methylphenylazid (77721-47-2) → Cresidine (120-71-8)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1016/S0040-4039(00)92160-9

Reference yield: 91.0%

2-Methoxi-5-methylphenylazid (77721-47-2) + exo-3,4-diazotricyclo[4.2.1.02,5]nona-3,7-diene (23979-29-5) → C15H17N5O (65245-81-0,77788-49-9)

Guidance literature:

In toluene; at 80 ℃; for 5h;

upstream raw materials:

p-methylanizole

Downstream raw materials:

C₁₅H₁₇N₅O

Cresidine

Refernces

• 1、 Kita,Tohma,Inagaki,Hatanaka,Yakura. "A novel oxidative azidation of aromatic compounds with hypervalent iodine reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA) and trimethylsilyl azide". . p. 4321 - 4324. Retrieved 2007/10/02.