4-ACETYLAMINO-3-METHYL-BENZENESULFONYL CHLORIDE

Base Information Edit

Chemical Name:4-ACETYLAMINO-3-METHYL-BENZENESULFONYL CHLORIDE
CAS No.:14988-21-7
Molecular Formula:C9H10 Cl N O3 S
Molecular Weight:247.702
Hs Code.:2924299090
Mol file:14988-21-7.mol

Synonyms:m-Toluenesulfonylchloride, 4-acetamido- (6CI,8CI); 4-Acetylamino-3-methylbenzenesulfonylchloride

Suppliers and Price of 4-ACETYLAMINO-3-METHYL-BENZENESULFONYL CHLORIDE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-acetylamino-3-methyl-benzenesulfonyl chloride
10mg
$ 45.00

Sigma-Aldrich
4-acetylamino-3-methyl-benzenesulfonyl chloride AldrichCPR
100 mg
$ 144.00

Total 8 raw suppliers

Chemical Property of 4-ACETYLAMINO-3-METHYL-BENZENESULFONYL CHLORIDE Edit

Chemical Property:

Melting Point:159 °C
Boiling Point:416.3±38.0 °C(Predicted)
PKA:13.76±0.70(Predicted)
PSA：71.62000
Density:1.411±0.06 g/cm3(Predicted)
LogP:3.03470

Purity/Quality:

98%min ^*data from raw suppliers

4-acetylamino-3-methyl-benzenesulfonyl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-ACETYLAMINO-3-METHYL-BENZENESULFONYL CHLORIDE

There total 8 articles about 4-ACETYLAMINO-3-METHYL-BENZENESULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: sodium 4-(acetylamino)-3-methylbenzenesulfonate

: 14988-21-7
4-(acetylamino)-3-methylbenzenesulfonyl chloride

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.5h;

Reference yield: 38.0%

: 4-acetamido-3-methylbenzenesulfonic acid

: 14988-21-7
4-(acetylamino)-3-methylbenzenesulfonyl chloride

Guidance literature:: 4-acetamido-3-methylbenzenesulfonic acid; With sodium hydroxide; In pyridine; at 20 ℃; for 3h;

With thionyl chloride; In N,N-dimethyl-formamide; at -30 - 40 ℃; for 2h;
DOI:10.1016/j.bmcl.2012.01.047

Reference yield:

: pyridinium 4-(acetylamino)-3-methylbenzenesulfonate

: 14988-21-7
4-(acetylamino)-3-methylbenzenesulfonyl chloride

Guidance literature:: pyridinium 4-(acetylamino)-3-methylbenzenesulfonate; With sodium hydroxide; at 20 ℃; for 5h;

With thionyl chloride; In N,N-dimethyl-formamide; at -10 ℃;
DOI:10.1016/j.ejmech.2021.113794