DIAMMINEDINITROPLATINUM(II)

Base Information

• Chemical Name: DIAMMINEDINITROPLATINUM(II)
• CAS No.: 14286-03-4
• Molecular Formula: H₆N₄O₆Pt
• Molecular Weight: 353.151
• Mol file: 14286-03-4.mol

Synonyms:Platinum,diamminebis(nitrato-O)-; Platinum, dinitratodiammine- (7CI); Diamminedinitratoplatinum

Chemical Property of DIAMMINEDINITROPLATINUM(II)

Chemical Property:

• PSA: 111.46000
• Density: 1.015g/mLat25℃
• LogP: 1.14900

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIAMMINEDINITROPLATINUM(II)

There total 13 articles about DIAMMINEDINITROPLATINUM(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

cis-diaminediiodoplatinum(II) + silver nitrate → cis-diaminedinitroplatinum(II) (41575-87-5,14286-03-4,74006-35-2)

Guidance literature:

With hydrogenchloride; In water; byproducts: AgCl; addn. of aq. AgNO3 to a suspn. of Pt-complex in water, heating at 70°C in the dark for 30 min; cooling, filtn. through celite, treating with two drops of aq. HCl to check the absence of silver, filtn., evapn. of filtrate to dryness, redissolution of residue in water with heating, filtn., evapn. to dryness, elem. anal.;

Reference yield: 84.0%

cis-diamminediiodoplatinum (II) (13841-96-8,15978-93-5,15978-94-6) + silver nitrate → {Pta2(NO3)2} (74006-35-2,41575-87-5,14286-03-4)

Guidance literature:

In water; for 2h; Inert atmosphere;

DOI:10.1016/j.ica.2014.11.017

Reference yield: 82.0%

cisplatin (15663-27-1) → cis-diaminedinitroplatinum(II) (41575-87-5,14286-03-4,74006-35-2) + cis-diamminechloro(nitrato)platinum(II) (117228-94-1) + cis-{Pt(NH3)2(O1-DMF)Cl}(1+) (128707-47-1,160017-70-9,79084-70-1) + cis-{Pt(NH3)2(O1-DMF)2}(2+) + cis-{Pt(NH3)2(O1-DMF)(NO3)}(1+)

Guidance literature:

With AgNO₃; In N,N-dimethyl-formamide; byproducts: AgCl; reacting AgNO3 with Pt complex in DMF (16 h, in the dark); centrifugation; detected by 195 Pt NMR;

DOI:10.1021/ja00160a044

upstream raw materials:

cisplatin

transplatin

trans-diiododiammineplatinum(II)

nitric acid

Downstream raw materials:

cisplatin

cis-diamminedibromoplatinum(II)

trans-diamminetetrachloroplatinum(IV)

cis-diamminedithiocyanatoplatinum(II)

Refernces

• 1、 Cheng, Junjie,Dai, Yi,Huang, Hai,Liu, Yangzhong,Shen, Ai-Zong,Zhu, Yang. "Combating metastasis of breast cancer cells with a carboplatin analogue containing an all-trans retinoic acid ligand". . p. 5039 - 5043. Retrieved 2020.
• 2、 -. "CARRIER THAT TARGETS FUCOSYLATED MOLECULE-PRODUCING CELLS". Paragraph 0139. . Retrieved 2015/02/18.