2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate

Base Information

• Chemical Name: 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate
• CAS No.: 1112459-38-7
• Molecular Formula: C₅H₁₄NO*C₂₈H₁₉ClN₅O₅S₂
• Molecular Weight: 709.247
• Mol file: 1112459-38-7.mol

Synonyms:2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate

Chemical Property of 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate

There total 3 articles about 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C28H20ClN5O5S2 (1112459-57-0) + cholin hydroxide (123-41-1) → 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate (1112459-38-7)

Guidance literature:

In 1,4-dioxane; water;

Reference yield:

Capadenoson (544417-40-5) → 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate (1112459-38-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dmap / dichloromethane; N,N-dimethyl-formamide / 20 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

3: 1,4-dioxane; water

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; dmap; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

C32H28ClN5O5S2 → 2-Hydroxy-N,N,N-trimethylethanaminium 3-(2-{4-[2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}thio)-3,5-dicyanopyridin-4-yl]phenoxy}ethoxy) 3-oxopropanoate (1112459-38-7)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

2: 1,4-dioxane; water

With trifluoroacetic acid; In 1,4-dioxane; dichloromethane; water;

upstream raw materials:

C₂₈H₂₀ClN₅O₅S₂

cholin hydroxide

Capadenoson

Refernces