Bicyclo[2.2.1]heptane-2-methanol, 3-methyl-

Base Information

• Chemical Name: Bicyclo[2.2.1]heptane-2-methanol, 3-methyl-
• CAS No.: 6968-75-8
• Molecular Formula: C9H16O
• Molecular Weight: 140.225
• Hs Code.: 2906199090
• European Community (EC) Number: 230-188-1
• NSC Number: 66275
• DSSTox Substance ID: DTXSID40989840
• Nikkaji Number: J266.015F
• Mol file: 6968-75-8.mol

Synonyms:6968-75-8;Bicyclo[2.2.1]heptane-2-methanol, 3-methyl-;{3-methylbicyclo[2.2.1]heptan-2-yl}methanol;(3-methyl-2-bicyclo[2.2.1]heptanyl)methanol;EINECS 230-188-1;3-Methyl-8,9,10-trinorborn-2-ylmethanol;(3-Methylbicyclo[2.2.1]heptan-2-yl)methanol;NSC66275;3-methylnorbornane-2-methanol;SCHEMBL1930484;3-methyl norcamphane-2-methanol;DTXSID40989840;2-hydroxymethyl-3-methylnorbornane;NSC 66275;NSC-66275;FT-0616072;2-hydroxymethyl-3-methylbicyclo[2.2.1]heptane

Chemical Property of Bicyclo[2.2.1]heptane-2-methanol, 3-methyl-

Chemical Property:

• Vapor Pressure: 0.0284mmHg at 25°C
• Refractive Index: 1.485
• Boiling Point: 217.4 °C at 760 mmHg
• Flash Point: 90.6 °C
• PSA: 20.23000
• Density: 0.975 g/cm³
• LogP: 1.66090
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 140.120115130
• Heavy Atom Count: 10
• Complexity: 133

Purity/Quality:

99%min ^*data from raw suppliers

3-METHYLNORBORNANE-2-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C2CCC(C2)C1CO

Technology Process of Bicyclo[2.2.1]heptane-2-methanol, 3-methyl-

There total 17 articles about Bicyclo[2.2.1]heptane-2-methanol, 3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-methylnorborn-5-ene-2-methanol (20529-84-4) → 2-hydroxymethyl-3-methyl-bicyclo[2.2.1]heptane (6968-75-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In diethyl ether; Product distribution / selectivity;

Reference yield:

2-formyl-3-methyl-5-norbornene (6465-95-8) → 2-hydroxymethyl-3-methyl-bicyclo[2.2.1]heptane (6968-75-8)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄

2: H₂ / Ni

With sodium tetrahydroborate; hydrogen; nickel;

Reference yield:

bi(cyclopentadiene) (77-73-6,933-60-8,1755-01-7,25038-78-2) + crotonaldehyde (123-73-9,4170-30-3) → 2-hydroxymethyl-3-methyl-bicyclo[2.2.1]heptane (6968-75-8)

Guidance literature:

bi(cyclopentadiene); crotonaldehyde; at 170 ℃; for 3h;

With nickel; at 150 ℃; for 4h; under 7500.75 Torr;

upstream raw materials:

acetic acid-(3-methyl-norborn-5-en-2-ylmethyl ester)

3-methylnorborn-5-ene-2-methanol

cyclopenta-1,3-diene

2-formyl-3-methyl-5-norbornene

Downstream raw materials:

santene

2-methylene-3-methylbicyclo[2.2.1]heptane

Refernces

• 1、 -. "PROCESS FOR THE PREPARATION OF BETA-SANTALOL AND DERIVATIVES THEREOF". Page/Page column 25. . Retrieved 2009/12/27.
• 2、 -. "Traction drive fluid, process for producing the same and bicyclo octane compound". . . Retrieved 2008/06/13.