C₄₈H₇₅NO₁₄

Base Information

• Chemical Name: C₄₈H₇₅NO₁₄
• CAS No.: 1416779-90-2
• Molecular Formula: C₄₈H₇₅NO₁₄
• Molecular Weight: 890.122
• Mol file: 1416779-90-2.mol

Synonyms:C₄₈H₇₅NO₁₄

Chemical Property of C₄₈H₇₅NO₁₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₈H₇₅NO₁₄

There total 7 articles about C₄₈H₇₅NO₁₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

C60H89NO19 (1416780-05-6) → C48H75NO14 (1416779-90-2)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jm301248y

Reference yield:

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-(((2R,3R,4S,5S,6S)-4,5-diacetoxy-6-(methoxycarbonyl)-3-(((2R,3R,4S,5S,6S)-3,4,5-triacetoxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid (118342-92-0,118525-42-1) → C48H75NO14 (1416779-90-2)

Guidance literature:

Multi-step reaction with 5 steps

1: triethylamine / tetrahydrofuran / 0.5 h / -5 °C / Inert atmosphere

2: sodium tetrahydroborate / water / 4.5 h / 10 - 20 °C / Inert atmosphere

3: pyridinium chlorochromate / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

4: acetic acid; sodium cyanoborohydride / methanol / 3 h / 20 °C / pH Ca_. 6 / Inert atmosphere

5: potassium hydroxide / water; ethanol / 1 h / 20 °C / Inert atmosphere

With sodium tetrahydroborate; sodium cyanoborohydride; acetic acid; triethylamine; pyridinium chlorochromate; potassium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; water;

DOI:10.1021/jm301248y

Reference yield:

C54H78O20 (1416779-82-2) → C48H75NO14 (1416779-90-2)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridinium chlorochromate / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

2: acetic acid; sodium cyanoborohydride / methanol / 3 h / 20 °C / pH Ca_. 6 / Inert atmosphere

3: potassium hydroxide / water; ethanol / 1 h / 20 °C / Inert atmosphere

With sodium cyanoborohydride; acetic acid; pyridinium chlorochromate; potassium hydroxide; In methanol; ethanol; dichloromethane; water;

DOI:10.1021/jm301248y

upstream raw materials:

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-(((2R,3R,4S,5S,6S)-4,5-diacetoxy-6-(methoxycarbonyl)-3-(((2R,3R,4S,5S,6S)-3,4,5-triacetoxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

C₅₄H₇₈O₂₀

glycyrrizhin

(3β,20β)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-glucopyranuronosyl-β-D-glucopyranosiduronic acid 6′ ,6′’-dimethyl ester

Refernces