10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine

Base Information

• Chemical Name: 10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine
• CAS No.: 146036-45-5
• Molecular Formula: C₃₆H₄₆N₂O₁₂
• Molecular Weight: 698.767
• Mol file: 146036-45-5.mol

Synonyms:10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine

Chemical Property of 10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine

There total 2 articles about 10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-(benzyloxycarbonylamino)propanoic acid (2304-94-1) + ryanodine (15662-33-6,97588-26-6,150736-85-9) → 10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine (146036-45-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 4 ℃; for 8h;

DOI:10.1021/jm00062a003

Reference yield: 1.4%

3-(benzyloxycarbonylamino)propanoic acid (2304-94-1) + ryanodine (15662-33-6,97588-26-6,150736-85-9) → 10-O-(3-benzoyloxycarbamoylpropionyl)ryanodine (146036-45-5) + 12-O-(3-benzoyloxycarbamoylpropionyl)anhydroryanodine + 10-O-(3-benzoyloxycarbamoylpropionyl)anhydroryanodine + 12-O-(3-benzoyloxycarbamoylpropionyl)ryanodine

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In tetrahydrofuran; for 42h;

DOI:10.1002/(SICI)1096-9063(199812)54:4<345::AID-PS825>3.0.CO;2-H

upstream raw materials:

3-(benzyloxycarbonylamino)propanoic acid

ryanodine

Refernces

• 1、 Bidasee,Besch Jr.,Kwon,Emmick,Besch,Gerzon,Humerickhouse. "C10-O(eq)-N-(4-azido-5-125iodo salicyloyl)-β-alanyl-β-alanyl ryanodine (Az-βAR), a novel photo-affinity ligand for the ryanodine binding site". . p. 33 - 47. Retrieved 2007/10/02.