3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate

Base Information

• Chemical Name: 3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate
• CAS No.: 1268449-61-1
• Molecular Formula: C₁₆H₁₁ClN₂OS₂
• Molecular Weight: 346.861
• Mol file: 1268449-61-1.mol

Synonyms:3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate

Chemical Property of 3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate

There total 2 articles about 3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

carbon disulfide (75-15-0,12122-00-8) + 2-pyridin-1-ium-1-ylacetonitrile chloride (17281-59-3) + 4-chlorobenzoylmethyl bromide (536-38-9) → 3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate (1268449-61-1)

Guidance literature:

carbon disulfide; 2-pyridin-1-ium-1-ylacetonitrile chloride; With sodium hydroxide; In ethanol; water; for 0.333333h; Cooling with ice;

4-chlorobenzoylmethyl bromide; In ethanol; water; at 20 ℃; for 4h;

at 60 - 80 ℃; under 3 Torr; neat (no solvent);

DOI:10.1248/cpb.58.1502

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 2-pyridin-1-ium-1-ylacetonitrile chloride (17281-59-3) + 4-chlorobenzoylmethyl bromide (536-38-9) → C16H11ClN2OS2 + 3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate (1268449-61-1)

Guidance literature:

carbon disulfide; 2-pyridin-1-ium-1-ylacetonitrile chloride; With sodium hydroxide; In ethanol; water; for 0.333333h; Cooling with ice;

4-chlorobenzoylmethyl bromide; In ethanol; water; at 20 ℃; for 4h;

DOI:10.1248/cpb.58.1502

Reference yield:

3-amino-2-(4-chlorobenzoyl)-4-(1-pyridinio)thiophene-5-thiolate (1268449-61-1) + 1-bromomethyl-4-bromobenzene (589-15-1) → Br(1-)*C23H17BrClN2OS2(1+)

Guidance literature:

In chloroform; at 50 ℃;

DOI:10.1248/cpb.58.1502

upstream raw materials:

carbon disulfide

2-pyridin-1-ium-1-ylacetonitrile chloride

4-chlorobenzoylmethyl bromide

Refernces