1-(2-(Phenanthren-9-yl)phenyl)propan-2-one

Base Information

• Chemical Name: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one
• CAS No.: 1013933-56-6
• Molecular Formula: C₂₃H₁₈O
• Molecular Weight: 310.395
• Mol file: 1013933-56-6.mol

Synonyms:2-(9-phenanthryl)phenylacetone

Chemical Property of 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one

Chemical Property:

• Boiling Point: 489.6±24.0 °C(Predicted)
• Density: 1.152±0.06 g/cm3(Predicted)
• Solubility.: DCM, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

1-(2-(Phenanthren-9-yl)phenyl)propan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one is an metabolite of Dibenzo[def,p]chrysene (D416945), an well known polycyclic aromatics hydrocarbons found in hot mix asphalt paving workers and the most potent tumorigen that has been identified to date.

Technology Process of 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one

There total 1 articles about 1-(2-(Phenanthren-9-yl)phenyl)propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(2-bromophenyl)propane-2-one (21906-31-0) + 9-phenanthrenylboronic acid (68572-87-2) → 2-(9-phenanthryl)phenylacetone (1013933-56-6)

Guidance literature:

1-(2-bromophenyl)propane-2-one; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; at 20 ℃; for 0.333333h; Inert atmosphere;

9-phenanthrenylboronic acid; In 1,2-dimethoxyethane; ethanol; for 8h; Reflux; Inert atmosphere;

DOI:10.1021/ol7029323

Reference yield: 74.0%

2-(9-phenanthryl)phenylacetone (1013933-56-6) → 9-methylbenzo[g]chrysene (13322-53-7)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 20 ℃; for 36h; Time; Temperature; Reagent/catalyst; chemoselective reaction; Reactivity; Inert atmosphere;

DOI:10.1021/ol7029323

upstream raw materials:

1-(2-bromophenyl)propane-2-one

9-phenanthrenylboronic acid

Downstream raw materials:

9-methylbenzo[g]chrysene

Refernces