N-carbobenzoxy-L-leucine 4-nitrobenzyl ester

Base Information

• Chemical Name: N-carbobenzoxy-L-leucine 4-nitrobenzyl ester
• CAS No.: 40299-11-4
• Molecular Formula: C₂₁H₂₄N₂O₆
• Molecular Weight: 400.431
• Mol file: 40299-11-4.mol

Synonyms:N-carbobenzoxy-L-leucine 4-nitrobenzyl ester

Chemical Property of N-carbobenzoxy-L-leucine 4-nitrobenzyl ester

Chemical Property:

Purity/Quality:

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Technology Process of N-carbobenzoxy-L-leucine 4-nitrobenzyl ester

There total 2 articles about N-carbobenzoxy-L-leucine 4-nitrobenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Z-Leu-OH (2018-66-8) + 4-nitrobenzyl chloride (619-73-8) → N-carbobenzoxy-L-leucine 4-nitrobenzyl ester (40299-11-4)

Guidance literature:

With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1021/ja952220w

Reference yield:

Z-Leu-OH (2018-66-8) + 4-nitrobenzyl chloride (100-14-1) → N-carbobenzoxy-L-leucine 4-nitrobenzyl ester (40299-11-4)

Guidance literature:

With ethyl acetate; triethylamine;

DOI:10.1021/ja01530a041

Reference yield:

N-carbobenzoxy-L-leucine 4-nitrobenzyl ester (40299-11-4) → Z-Leu-OH (2018-66-8)

Guidance literature:

With antibody 7G₁₂; Tris buffer; water; In dimethyl sulfoxide; at 25 ℃; Rate constant;

DOI:10.1021/ja952220w

upstream raw materials:

Z-Leu-OH

4-nitrobenzyl chloride

4-nitrobenzyl chloride

Downstream raw materials:

L-leucine p-nitrobenzyl ester

Z-Leu-OH

Refernces