9-HYDROXY-1-FLUORENECARBOXYLIC ACID)

Base Information

• Chemical Name: 9-HYDROXY-1-FLUORENECARBOXYLIC ACID)
• CAS No.: 24018-33-5
• Molecular Formula: C₁₄H₁₀O₃
• Molecular Weight: 226.232
• Hs Code.: 2918290000
• Mol file: 24018-33-5.mol

Synonyms:Fluorene-1-carboxylicacid, 9-hydroxy- (8CI); 9-Hydroxyfluorene-1-carboxylic acid

Chemical Property of 9-HYDROXY-1-FLUORENECARBOXYLIC ACID)

Chemical Property:

• Vapor Pressure: 2.36E-09mmHg at 25°C
• Boiling Point: 462.6°Cat760mmHg
• Flash Point: 247.7°C
• PSA: 57.53000
• Density: 1.433g/cm³
• LogP: 2.44690

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-HYDROXY-1-FLUORENECARBOXYLIC ACID)

There total 4 articles about 9-HYDROXY-1-FLUORENECARBOXYLIC ACID) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.3%

9-oxo-9H-fluorene-1-carboxylic acid (1573-92-8) → 9-hydroxy-1-fluorene-carboxylic acid (24018-33-5)

Guidance literature:

With sodium tetrahydroborate; for 48h;

Reference yield:

biphenyl-2,3-dicarboxylic acid anhydride (954-06-3) → 9-hydroxy-1-fluorene-carboxylic acid (24018-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃ / benzene / Heating

2: NaBH₄, NaOH

With sodium hydroxide; sodium tetrahydroborate; aluminium trichloride; In benzene;

Reference yield:

fluoranthene (206-44-0) → 9-hydroxy-1-fluorene-carboxylic acid (24018-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: chromium (VI)-oxide; aqueous acetic acid

2: Raney nickel; aq.-ethanolic KOH-solution / Hydrogenation

With chromium(VI) oxide; potassium hydroxide; nickel; acetic acid;

DOI:10.1039/jr9480001137

upstream raw materials:

9-oxo-9H-fluorene-1-carboxylic acid

fluoranthene

biphenyl-2,3-dicarboxylic acid anhydride

Refernces

• 1、 Shashidhar, M. Srikantaiah,Bhatt, M. Vivekananda. "Aspects of Tautomerism. Part 15. Investigations on Oxo-participation in δ-Oxocarboxylic Acid Chlorides during their Formation and Alcoholysis". . p. 355 - 358. Retrieved 2007/10/02.