D-HOMOTYROSINE HYDROBROMIDE

Base Information

• Chemical Name: D-HOMOTYROSINE HYDROBROMIDE
• CAS No.: 185617-14-5
• Molecular Formula: BrH*C₁₀H₁₃NO₃
• Molecular Weight: 276.13
• Mol file: 185617-14-5.mol

Synonyms:Benzenebutanoicacid, a-amino-4-hydroxy-, hydrobromide,(R)-; Benzenebutanoic acid, a-amino-4-hydroxy-, hydrobromide, (aR)- (9CI)

Chemical Property of D-HOMOTYROSINE HYDROBROMIDE

Chemical Property:

• PSA: 83.55000
• LogP: 2.39510
• Storage Temp.: Store at 0-5°C

Purity/Quality:

99% ^*data from raw suppliers

D-Homotyrosinehydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of D-HOMOTYROSINE HYDROBROMIDE

There total 2 articles about D-HOMOTYROSINE HYDROBROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

N-(methylcarbamoyl)homotyrosine methyl ester (110936-12-4) → L-homotyrosine hydrobromide (141899-12-9,185617-14-5)

Guidance literature:

With hydrogen bromide; acetic acid; at 60 ℃; for 76h;

DOI:10.1021/jm00093a018

Reference yield:

(2R)-2-<(methoxycarbonyl)amino>-4-(4-methoxyphenyl)-butanoic acid (110936-09-9) → (R)-homotyrosine hydrobromide (185617-14-5)

Guidance literature:

In hydrogen bromide; acetic acid;

upstream raw materials:

N-(methylcarbamoyl)homotyrosine methyl ester

(2R)-2-<(methoxycarbonyl)amino>-4-(4-methoxyphenyl)-butanoic acid

Refernces

• 1、 Zambias, Robert A.,Hammond, Milton L.,Heck, James V.,Bartizal, Ken,Trainor, Charlotte,et al.. "Preparation and Structure-Activity Relationships of Simplified Analogues of the Antifungal Agent Cilofungin: A Total Synthesis Approach". . p. 2843 - 2855. Retrieved 2007/10/02.