C₂₆H₂₂Cl₂N₄O₅

Base Information

• Chemical Name: C₂₆H₂₂Cl₂N₄O₅
• CAS No.: 1424395-19-6
• Molecular Formula: C₂₆H₂₂Cl₂N₄O₅
• Molecular Weight: 541.39
• Mol file: 1424395-19-6.mol

Synonyms:C₂₆H₂₂Cl₂N₄O₅

Chemical Property of C₂₆H₂₂Cl₂N₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₂₂Cl₂N₄O₅

There total 5 articles about C₂₆H₂₂Cl₂N₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C27H24Cl2N4O5 (1424395-11-8) → C26H22Cl2N4O5 (1424395-19-6)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran; methanol;

DOI:10.1016/j.bmcl.2012.12.043

Reference yield:

3-pyridinecarboxaldehyde (500-22-1) → C26H22Cl2N4O5 (1424395-19-6)

Guidance literature:

Multi-step reaction with 5 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol / 20 °C

2: sodium hypochlorite / tetrahydrofuran / 20 °C

3: lithium hydroxide; water / tetrahydrofuran; methanol

4: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide

5: lithium hydroxide; water / tetrahydrofuran; methanol

With 4-methyl-morpholine; sodium hypochlorite; hydroxylamine hydrochloride; water; sodium acetate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.12.043

Reference yield:

3-pyridinealdoxime (1193-92-6) → C26H22Cl2N4O5 (1424395-19-6)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hypochlorite / tetrahydrofuran / 20 °C

2: lithium hydroxide; water / tetrahydrofuran; methanol

3: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide

4: lithium hydroxide; water / tetrahydrofuran; methanol

With 4-methyl-morpholine; sodium hypochlorite; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

DOI:10.1016/j.bmcl.2012.12.043

upstream raw materials:

C₂₇H₂₄Cl₂N₄O₅

3-pyridinecarboxaldehyde

3-pyridinealdoxime

C₁₁H₁₂N₂O₃

Refernces