BENZENEMETHANESULFONYL CHLORIDE, 3-METHOXY-

Base Information

• Chemical Name: BENZENEMETHANESULFONYL CHLORIDE, 3-METHOXY-
• CAS No.: 163295-76-9
• Molecular Formula: C8H9 Cl O3 S
• Molecular Weight: 220.677
• Mol file: 163295-76-9.mol

Synonyms:(3-Methoxyphenyl)methanesulfonylchloride; 3-Methoxybenzylsulfonyl chloride

Chemical Property of BENZENEMETHANESULFONYL CHLORIDE, 3-METHOXY-

Chemical Property:

• PSA: 51.75000
• LogP: 2.84460

Purity/Quality:

99% ^*data from raw suppliers

(3-Methoxyphenyl)methanesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZENEMETHANESULFONYL CHLORIDE, 3-METHOXY-

There total 4 articles about BENZENEMETHANESULFONYL CHLORIDE, 3-METHOXY- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

→ (3-methoxyphenyl)methanesulfonyl chloride (163295-76-9)

Guidance literature:

Reference yield: 65.0%

(3-methoxyphenyl)methanesulfonic acid → (3-methoxyphenyl)methanesulfonyl chloride (163295-76-9)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl-formamide; at -20 - 20 ℃; for 2.5h;

Reference yield:

sodium; (3-methoxy-phenyl)-methanesulfonate → (3-methoxyphenyl)methanesulfonyl chloride (163295-76-9)

Guidance literature:

With thionyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1055/s-2005-872164

upstream raw materials:

1-bromomethyl-3-methoxybenzene

Downstream raw materials:

C₂₄H₂₂F₅NO₇S

C₁₄H₁₀F₅NO₃S

(3-Methoxy-phenyl)-methanesulfonic acid (3aR,5R,6R,6aR)-5-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester

Refernces

• 1、 Enders, Dieter,Adelbrecht, Jean-Claude,Harnying, Wacharee. "Asymmetric synthesis of α- and α,β-substituted β-alkoxycarbonyl sulfonates". . p. 2962 - 2968. Retrieved 2007/10/03.