4-(PERFLUOROOCTYL)BENZYL ALCOHOL

Base Information

• Chemical Name: 4-(PERFLUOROOCTYL)BENZYL ALCOHOL
• CAS No.: 163114-33-8
• Molecular Formula: C15H7 F17 O
• Molecular Weight: 526.193
• Mol file: 163114-33-8.mol

Synonyms:Benzenemethanol,4-(heptadecafluorooctyl)- (9CI)

Chemical Property of 4-(PERFLUOROOCTYL)BENZYL ALCOHOL

Chemical Property:

• Boiling Point: 285.1±40.0 °C(Predicted)
• PKA: 13.99±0.10(Predicted)
• PSA: 20.23000
• Density: 1.599±0.06 g/cm3(Predicted)
• LogP: 6.64480

Purity/Quality:

98%min ^*data from raw suppliers

4-(PERFLUOROOCTYL)BENZYL ALCOHOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(PERFLUOROOCTYL)BENZYL ALCOHOL

There total 5 articles about 4-(PERFLUOROOCTYL)BENZYL ALCOHOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 4-perfluorooctylbenzoate (80791-12-4) → (4-Heptadecafluorooctyl-phenyl)-methanol (163114-33-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(97)00272-X

Reference yield: 87.0%

ethyl 4-perfluorooctylbenzoate (83766-59-0) → (4-Heptadecafluorooctyl-phenyl)-methanol (163114-33-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h;

DOI:10.1039/b516487g

Reference yield:

1-iodoheptadecafluorooctane (507-63-1) → (4-Heptadecafluorooctyl-phenyl)-methanol (163114-33-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Cu / dimethylsulfoxide / 24 h / 120 °C

2: 87 percent / LiAlH₄ / tetrahydrofuran / 1 h / 0 °C

With lithium aluminium tetrahydride; copper; In tetrahydrofuran; dimethyl sulfoxide;

DOI:10.1039/b516487g

upstream raw materials:

methyl 4-perfluorooctylbenzoate

ethyl 4-perfluorooctylbenzoate

1-iodoheptadecafluorooctane

4-iodobenzoic acid ethyl ester

Downstream raw materials:

4-(perfluoro-n-octyl)benzyl bromide

C₃₂H₂₇BF₁₇NO₄

4-heptadecafluorooctylbenzaldehyde

Refernces

• 1、 Pozzi, Gianluca,Colombani, Ida,Miglioli, Massimo,Montanari, Fernando,Quici, Silvio. "Epoxidation of alkenes under liquid-liquid biphasic conditions: Synthesis and catalytic activity of Mn(III)-tetraarylporphyrins bearing perfluoroalkyl tails". . p. 6145 - 6162. Retrieved 2007/10/03.