N-methylcyclooctanamine

Base Information

• Chemical Name: N-methylcyclooctanamine
• CAS No.: 40221-52-1
• Molecular Formula: C9H19N
• Molecular Weight: 141.25
• Hs Code.: 2921300090
• European Community (EC) Number: 665-004-2
• DSSTox Substance ID: DTXSID90400151
• Wikidata: Q72460236
• Mol file: 40221-52-1.mol

Synonyms:N-methylcyclooctanamine;40221-52-1;N-METHYLCYCLOOCTANAMINE HCL;Cyclooctyl-methyl-amine;Cyclooctanamine, N-methyl-;SCHEMBL1485899;DTXSID90400151;AKOS000132329;AS-58546;FT-0639624;EN300-61112;L10188;Z102766896

Chemical Property of N-methylcyclooctanamine

Chemical Property:

• Refractive Index: 1.4740
• Boiling Point: 194.5 °C at 760 mmHg
• PKA: 11.25±0.20(Predicted)
• Flash Point: 66.3 °C
• PSA: 12.03000
• Density: 0.847 g/cm³
• LogP: 2.70960
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 141.151749610
• Heavy Atom Count: 10
• Complexity: 72.8

Purity/Quality:

99% ^*data from raw suppliers

N-methylcyclooctanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1CCCCCCC1

Technology Process of N-methylcyclooctanamine

There total 3 articles about N-methylcyclooctanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ cyclooctyl-methyl-amine (40221-52-1)

Guidance literature:

With ethanol; sodium;

DOI:10.1021/ja01161a068

Reference yield:

methanol (67-56-1) + cycloactanone (502-49-8) + methylamine (74-89-5) → cyclooctyl-methyl-amine (40221-52-1)

Guidance literature:

With nickel; at 100 - 120 ℃; under 58840.6 Torr; Hydrogenation;

Reference yield:

cycloactanone (502-49-8) + methylamine (74-89-5) → cyclooctyl-methyl-amine (40221-52-1)

Guidance literature:

With hydrogenchloride; cyano-borane; compound with lithium hydride; In methanol;

DOI:10.1021/ja00741a013

upstream raw materials:

methanol

cycloactanone

methylamine

Downstream raw materials:

2-hydroxy-3-chloro-5-methyl-N-methyl-N-cyclooctyl-benzylamine

N-Methyl-N-cyclooctyl-N'-guanyl-aethylendiamin

N-Cyclooctyl-4-(3-formyl-4-nitro-phenoxy)-N-methyl-butyramide

9-methyl-9-aza-bicyclo[3.3.1]nonane

Refernces

• 1、 Matzel, Philipp,Krautschick, Lukas,H?hne, Matthias. "Photometric Characterization of the Reductive Amination Scope of the Imine Reductases from Streptomyces tsukubaensis and Streptomyces ipomoeae". . p. 2022 - 2027. Retrieved 2017/10/07.