6-AMINO-BENZOOXAZOLE-2-THIOL

Base Information

• Chemical Name: 6-AMINO-BENZOOXAZOLE-2-THIOL
• CAS No.: 4694-92-2
• Molecular Formula: C7H6 N2 O S
• Molecular Weight: 166.2
• Hs Code.: 2934999090
• Mol file: 4694-92-2.mol

Synonyms:2-Benzoxazolethiol,6-amino- (6CI,7CI,8CI); 6-Amino-2-mercaptobenzoxazole

Chemical Property of 6-AMINO-BENZOOXAZOLE-2-THIOL

Chemical Property:

• Vapor Pressure: 6.31E-05mmHg at 25°C
• Refractive Index: 1.755
• Boiling Point: 345.1°Cat760mmHg
• Flash Point: 162.5°C
• PSA: 90.85000
• Density: 1.452g/cm³
• LogP: 2.27990

Purity/Quality:

98%Min ^*data from raw suppliers

6-Amino-benzooxazole-2-thiol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-AMINO-BENZOOXAZOLE-2-THIOL

There total 6 articles about 6-AMINO-BENZOOXAZOLE-2-THIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Mercapto-6-nitrobenzoxazole (14541-93-6) → 6‐aminobenzo[d]oxazole‐2‐thiol (4694-92-2)

Guidance literature:

With sodiumsulfide nonahydrate; In ethanol; water; at 90 ℃; for 4h;

DOI:10.1002/ardp.201800313

Reference yield:

6-nitrobenzo[d]oxazole-2(3H)-thione (14541-93-6) → 6-aminobenzo[d]oxazole-2(3H)-thione (4694-92-2)

Guidance literature:

With sodium hydroxide; sodium dithionite;

Reference yield:

5-Nitro-2-aminophenol (121-88-0) → 6-aminobenzo[d]oxazole-2(3H)-thione (4694-92-2)

Guidance literature:

Multi-step reaction with 2 steps

2: iron; aqueous HCl

With hydrogenchloride; iron;

DOI:10.1021/jo01370a010

upstream raw materials:

6-nitrobenzo[d]oxazole-2(3H)-thione

diamino-2,5 phenol

5-Nitro-2-aminophenol

2-Mercapto-6-nitrobenzoxazole

Downstream raw materials:

2-benzylmercapto-benzoxazol-6-ylamine

4-amino-N-(2-thioxo-2,3-dihydro-benzooxazol-6-yl)-benzenesulfonamide

[4-(2-thioxo-2,3-dihydro-benzooxazol-6-ylsulfamoyl)-phenyl]-carbamic acid methyl ester

Refernces